Spinal injuries: In search of a miracle

被引:14
作者
Pearson, H
机构
关键词
D O I
10.1038/423112a
中图分类号
O [数理科学和化学]; P [天文学、地球科学]; Q [生物科学]; N [自然科学总论];
学科分类号
07 ; 0710 ; 09 ;
摘要
Paralysed patients are looking to scientists working on spinal-cord regeneration to help them walk again. Is this pressure causing too much faith to be placed in preliminary, inconclusive results? Helen Pearson investigates.
引用
收藏
页码:112 / 113
页数:2
相关论文
共 8 条
[1]   Spinal cord repair in adult paraplegic rats: Partial restoration of hind limb function [J].
Cheng, H ;
Cao, YH ;
Olson, L .
SCIENCE, 1996, 273 (5274) :510-513
[2]   Axon regeneration in young adult mice lacking Nogo-A/B [J].
Kim, JE ;
Li, SX ;
GrandPré, T ;
Qiu, D ;
Strittmatter, SM .
NEURON, 2003, 38 (02) :187-199
[3]   Peripheral nerve grafts and aFGF restore partial hindlimb function in adult paraplegic rats [J].
Lee, YS ;
Hsiao, I ;
Lin, VW .
JOURNAL OF NEUROTRAUMA, 2002, 19 (10) :1203-1216
[4]   Functional recovery of paraplegic rats and motor axon regeneration in their spinal cords by olfactory ensheathing glia [J].
Ramón-Cueto, A ;
Cordero, MI ;
Santos-Benito, FF ;
Avila, J .
NEURON, 2000, 25 (02) :425-435
[5]   Implantation of stimulated homologous macrophages results in partial recovery of paraplegic rats [J].
Rapalino, O ;
Lazarov-Spiegler, O ;
Agranov, E ;
Velan, GJ ;
Yoles, E ;
Fraidakis, M ;
Solomon, A ;
Gepstein, R ;
Katz, A ;
Belkin, M ;
Hadani, M ;
Schwartz, M .
NATURE MEDICINE, 1998, 4 (07) :814-821
[6]   AXONS FROM CNS NEURONS REGENERATE INTO PNS GRAFTS [J].
RICHARDSON, PM ;
MCGUINNESS, UM ;
AGUAYO, AJ .
NATURE, 1980, 284 (5753) :264-265
[7]   Systemic deletion of the myelin-associated outgrowth inhibitor Nogo-A improves regenerative and plastic responses after spinal cord injury [J].
Simonen, M ;
Pedersen, V ;
Weinmann, O ;
Schnell, L ;
Buss, A ;
Ledermann, B ;
Christ, F ;
Sansig, G ;
van der Putten, H ;
Schwab, ME .
NEURON, 2003, 38 (02) :201-211
[8]   Lack of enhanced spinal regeneration in Nogo-deficient mice [J].
Zheng, BH ;
Ho, C ;
Li, SX ;
Keirstead, H ;
Steward, O ;
Tessier-Lavigne, M .
NEURON, 2003, 38 (02) :213-224