Drug treatment of hypertension: the reduction of pulse pressure does not necessarily parallel that of systolic and diastolic blood pressure

被引：27

作者：

Safar, ME

Rudnichi, A

Asmar, R

机构：

[1] Hop Broussais, Dept Internal Med, Paris, France

[2] Hop Broussais, INSERM, U337, Paris, France

[3] Inst Cardiovasc, Paris, France

来源：

JOURNAL OF HYPERTENSION | 2000年 / 18卷 / 09期

关键词：

antihypertensive therapy; pulse pressure; cardiovascular risk;

D O I：

10.1097/00004872-200018090-00001

中图分类号：

R6 [外科学];

学科分类号：

1002 ; 100210 ;

摘要：

Drug treatment of hypertension reduces systolic and diastolic blood pressure according to a well-established dose-response curve. Whether there is a parallel decrease in mean blood pressure and pulse pressure has not been investigated in the past. Recent analysis of the literature and personal work indicates that, during drug treatment of hypertension, a significant decrease in systolic and diastolic blood pressure may be associated with an unchanged pulse pressure, a situation that might contribute to maintaining cardiovascular risk. J Hypertens 2000, 18:1159-1163 (C) Lippincott Williams & Wilkins.

引用

收藏

页码：1159 / 1163

页数：5

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