In vitro activity of a new 8-methoxyquinolone, BAY 12-8039, against Chlamydia pneumoniae

被引：35

作者：

Roblin, PM ^{[1
]}

Hammerschlag, MR ^{[1
]}

机构：

[1] SUNY Hlth Sci Ctr, Dept Pediat, Div Infect Dis, Brooklyn, NY 11203 USA

来源：

ANTIMICROBIAL AGENTS AND CHEMOTHERAPY | 1998年 / 42卷 / 04期

关键词：

D O I：

10.1128/AAC.42.4.951

中图分类号：

Q93 [微生物学];

学科分类号：

071005 ; 100705 ;

摘要：

The in vitro susceptibilities of 10 strains of Chlamydia pneumoniae to a new 8-methoxyquinolone, BAY 12-8039, and to ofloxacin, doxycycline, and erythromycin were determined. The activity of BAY 12-8039 was similar to that of ofloxacin, with a MIC at which 90% of the isolates had no inclusions and a minimal chlamydicidal concentration at which 90% of the isolates had no inclusions after passage of 1.0 mu g/ml, but this activity was less than those of doxycycline and erythromycin.

引用

页码：951 / 952

页数：2

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