Biology of personality dimensions

被引：58

作者：

Cloninger, CR

机构：

[1] Washington Univ, Sch Med, Dept Psychiat, St Louis, MO 63110 USA

[2] Washington Univ, Sch Med, Dept Genet, St Louis, MO 63110 USA

来源：

CURRENT OPINION IN PSYCHIATRY | 2000年 / 13卷 / 06期

关键词：

D O I：

10.1097/00001504-200011000-00024

中图分类号：

R749 [精神病学];

学科分类号：

100205 ;

摘要：

Rapid progress is being made in understanding the neurobiology of human personality. This has been facilitated by using self-report questionnaires that assess multiple dimensions of personality quantitatively and reliably. Hypothesis-driven research has mapped models with five to seven dimensions of personality to results from brain imaging, neurophysiology, neurochemistry, and molecular genetics. At each level of organization there are non-linear interactions among multiple variables. Even at the molecular genetic level, each personality dimension is influenced by epistatic interactions among a family of genes, and the sets influencing each trait are partially specific and partially overlapping. What emerges is a picture of self-organizing complexity appropriate for psychobiological systems that involve adaptation to an ever-changing environment. Curr Opin Psychiatry 13:611-616 (C) 2000 Lippincott Williams & Wilkins.

引用

页码：611 / 616

页数：6

共 59 条

[1] An interaction between the catechol O-methyltransferase and serotonin transporter promoter region polymorphisms contributes to Tridimensional Personality Questionnaire persistence scores in normal subjects [J].