Antimicrobial biomaterials and their potential application in ophthalmology

被引:5
作者
Anaya-Alaminos, Roberto [1 ]
Ibanez-Flores, Nuria [1 ]
Aznar-Pena, Irene [1 ]
Gonzalez-Andrades, Miguel [2 ,3 ]
机构
[1] Inst Catala Retina, Dept Orbital & Ophthalm Plast Surg, Carrer Ganduxer 117, Barcelona 08022, Spain
[2] Harvard Univ, Massachusetts Eye & Ear Infirm, Sch Med, Dept Ophthalmol,Boston Keratoprosthesis Lab, Boston, MA USA
[3] Harvard Univ, Schepens Eye Res Inst, Sch Med, Boston, MA USA
关键词
Antimicrobial biomaterials; Implant-associated infections; Ophthalmology; PEPTIDE NUCLEIC-ACID; INTRAOCULAR-LENS; PSEUDOMONAS-AERUGINOSA; SILVER NANOPARTICLES; CATARACT-SURGERY; BIOFILM; PREVENTION; INFECTION; EFFICACY; GROWTH;
D O I
10.5301/jabfm.5000253
中图分类号
Q6 [生物物理学];
学科分类号
071011 [生物物理学];
摘要
Infections associated with the use of intraocular, periocular, or orbital implants are associated with an increase in both morbidity and in the costs of ophthalmological surgery. This is due to an increased number of visits and the need for additional treatments, at a time when some conventional therapies are losing their efficacy, or even hospitalization. To avoid such consequences, the first step should be to prevent the biomaterials that form implants from being colonized by various microorganisms, either intraoperatively or postoperatively. To this end, several lines of research have emerged that aim at equipping implants with antimicrobial properties, some of which are described in this review.
引用
收藏
页码:E346 / E350
页数:5
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