Role of cytokines in heart failure

被引：124

作者：

Blum, A ^{[1
]}

Miller, H ^{[1
]}

机构：

[1] Tel Aviv Med Ctr, Dept Cardiol, IL-64239 Tel Aviv, Israel

来源：

AMERICAN HEART JOURNAL | 1998年 / 135卷 / 02期

关键词：

D O I：

10.1016/S0002-8703(98)70080-8

中图分类号：

R5 [内科学];

学科分类号：

1002 [临床医学]; 100201 [内科学];

摘要：

Heart Failure is a complex neurohumoral and inflammatory syndrome. Studies have shown that proinflammatory cytokines (interleukin-1, interleukin-2, interleukin-6, and tumor necrosis factor) are involved in cardiac depression and in the complex syndrome of heart failure. Understanding the involvement of these cytokines may enable us to reverse cardiac depression and heart failure with the use of monoclonal antibodies directed against specific cytokines that may block the downhill progression of heart failure.

引用

页码：181 / 186

页数：6

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