Tetramethyl fluoro formamidinium hexafluorophosphate - An improved synthesis and some new uses.

被引：33

作者：

Boas, U

Pedersen, B

Christensen, JB

机构：

[1] Univ Copenhagen, CISMI, DK-2100 Copenhagen, Denmark

[2] Exiqon AS, DK-2950 Vedbaek, Denmark

来源：

SYNTHETIC COMMUNICATIONS | 1998年 / 28卷 / 07期

关键词：

D O I：

10.1080/00397919808005964

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

A non-phosgene, cheap synthesis of Tetramethyl Fluoro Formamidinium Hexafluorophosphate (TFFH) has been developed, and TFFH has been shown to be an useful reagent for preparation of isothiocyanates and hydrazides.

引用

页码：1223 / 1231

页数：9

共 9 条

[1] NEW SYNTHESIS OF ALIPHATIC ISOTHIOCYANATES FROM PRIMARY AMINES, CONVENIENT FOR IN-SITU USE [J].

BOAS, U ;

JAKOBSEN, MH .

JOURNAL OF THE CHEMICAL SOCIETY-CHEMICAL COMMUNICATIONS, 1995, (19) :1995-1996

[2] Peptide synthesis via amino acid halides [J].

Carpino, LA ;

Beyermann, M ;

Wenschuh, H ;

Bienert, M .

ACCOUNTS OF CHEMICAL RESEARCH, 1996, 29 (06) :268-274

[3] TETRAMETHYLFLUOROFORMAMIDINIUM HEXAFLUOROPHOSPHATE - A RAPID-ACTING PEPTIDE COUPLING REAGENT FOR SOLUTION AND SOLID-PHASE PEPTIDE-SYNTHESIS [J].

CARPINO, LA ;

EL-FAHAM, A .

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 1995, 117 (19) :5401-5402

[4] O-BENZOTRIAZOLYL-N,N,N',N'-TETRAMETHYLURONIUM HEXAFLUOROPHOSPHATE AS COUPLING REAGENT FOR THE SYNTHESIS OF PEPTIDES OF BIOLOGICAL INTEREST [J].

DOURTOGLOU, V ;

GROSS, B ;

LAMBROPOULOU, V ;

ZIOUDROU, C .

SYNTHESIS-STUTTGART, 1984, (07) :572-574

[5] SYNTHESIS OF CARBOXYLIC ACID HYDRAZIDES AND S-TRIAZOLES OF THE ANTHRAQUINONE SERIES [J].

KLINGSBERG, E .

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 1958, 80 (21) :5786-5789

[6] REACTION OF 3,3-PENTAMETHYLENEDIAZIRIDINE WITH DIPHENYLCYCLOPROPENONE [J].

LOWN, JW .

JOURNAL OF THE CHEMICAL SOCIETY C-ORGANIC, 1969, (10) :1338-&

[7]

NAEGLELI C, 1928, HELV CHIM ACTA, V11, P621

[8] REACTIONS OF ISOTHIOCYANATES WITH 2-AMINO SUGARS - ELECTROPHORESIS IN BORATE AND TUNGSTATE BUFFERS, AND SPECTROSCOPY OF PRODUCTS [J].

SCOTT, JE .

CARBOHYDRATE RESEARCH, 1970, 14 (03) :389-&

[9]

Wieland H, 1927, LIEBIGS ANN CHEM, V452, P1

← 1 →