Rational design of novel photoinduced electron transfer type fluorescent probes for sodium cation

被引：32

作者：

Kenmoku, S

Urano, Y

Kanda, K

Kojima, H

Kikuchi, K

Nagano, T

机构：

[1] Univ Tokyo, Grad Sch Pharmaceut Sci, Bunkyo Ku, Tokyo 1130033, Japan

[2] JST Corp, Presto, Kawaguchi, Saitama 3320012, Japan

来源：

TETRAHEDRON | 2004年 / 60卷 / 49期

关键词：

photoinduced electron transfer; rational design; fluorescence probe; sodium cation;

D O I：

10.1016/j.tet.2004.06.108

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

We have developed novel fluorescence probes for sodium cation based on photoinduced electron transfer (PeT). In this study, we rationally designed new probes and succeeded in achieving fluorescence enhancement upon sodium ion binding by reducing the HOMO energy level of the chelator group within the probe molecule. Our new probes show low pH dependency, possibly because of their simple structures. Our results confirm the value of rational probe design based on PeT. (C) 2004 Elsevier Ltd. All rights reserved.

引用

页码：11067 / 11073

页数：7

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