Goal-directed, serial and synchronous activation of neurons in the primate striatum

被引：33

作者：

Kimura, M ^{[1
]}

Matsumoto, N ^{[1
]}

Okahashi, K ^{[1
]}

Ueda, Y ^{[1
]}

Satoh, T ^{[1
]}

Minamimoto, T ^{[1
]}

Sakamoto, M ^{[1
]}

Yamada, H ^{[1
]}

机构：

[1] Kyoto Prefectural Univ Med, Dept Physiol, Kamigyo Ku, Kyoto 6028566, Japan

来源：

NEUROREPORT | 2003年 / 14卷 / 06期

关键词：

cortico-basal ganglia loops; cross-correlation analysis; goal-directed planning; motor sequence; serial activation; striatum;

D O I：

10.1097/00001756-200305060-00004

中图分类号：

Q189 [神经科学];

学科分类号：

071006 [神经生物学];

摘要：

To study roles of cortico-basal ganglia loops in action planning, we examined interactions between the activities of simultaneously recorded neurons in the striatum of monkeys performing sequence motor tasks by cross-correlation analysis. Serial activation occurred between projection neurons in a motor sequence-dependent manner, and was in the direction of a neuron encoding an early event in the sequence to a neuron encoding the same event or later, but closer event to the reward. Synchronous activation occurred between pairs of interneurons. The serial activation seems to originate through the cortico-basal ganglia loops, because projection neurons are inhibitory. We propose that the task-dependent serial and synchronous activation of striate neurons may be a neural substrate for goal-directed planning through the basal ganglia.

引用

页码：799 / 802

页数：4

共 23 条

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