Preoperative right portal vein embolization in patients with metastatic liver disease - Metastatic liver volumes after RPVE

被引:56
作者
Barbaro, B
Stasi, CD
Nuzzo, G
Vellone, M
Giuliante, F
Marano, P
机构
[1] Univ Cattolica Sacro Cuore, Policlin Agostino Gemelli, Dept Radiol, IT-00168 Rome, Italy
[2] Univ Cattolica Sacro Cuore, Policlin Agostino Gemelli, Dept Surg, IT-00168 Rome, Italy
关键词
liver; hypertrophy; neoplasm; portal vein; interventional procedure; therapeutic blockade; CT;
D O I
10.1034/j.1600-0455.2003.00016.x
中图分类号
R8 [特种医学]; R445 [影像诊断学];
学科分类号
1002 ; 100207 ; 1009 ;
摘要
Purpose: To quantify liver metastases and future remnant liver (FRL) volumes in patients who underwent right portal vein embolization (RPVE) and to evaluate the effects of this procedure on metastase growth. Material and Methods: Nine patients with liver metastases from primary colon (n = 5), rectal lesions (n = 1) and carcinoid tumors (n = 3) underwent spiral CT to evaluate the ratio of the non-tumorous parenchymal volume of the resected liver to that of the whole liver volume (R2). Hand tracing was used to isolate the entire liver, the resected liver and metastase volumes. All patients with R2 > 60% underwent RPVE. Results: FRL exhibited a 101-336 cm(3) (average 241 cm(3)) increase in volume 1 month after RPVE. One patient refused surgery for 2 months and before surgery the increase in volume of the FRL was similar to that of other patients (180.64 cm(3)). Percent metastases volume from colorectal carcinoma in embolized liver parenchyma increased from 62.4% to 138.4% at 1 month and to 562% at 2 months after RPVE. Metastase volume from carcinoid tumors was unchanged. Conclusion: One month after RPVE, hypertrophy of the FRL is evident. In the embolized liver, there was a progressive increase in metastase volume from colorectal carcinoma while metastase volume from carcinoid tumor was unchanged in embolized and non-embolized liver.
引用
收藏
页码:98 / 102
页数:5
相关论文
共 9 条
[1]   During liver regeneration following right portal embolization the growth rate of liver metastases is more rapid than that of the liver parenchyma [J].
Elias, D ;
de Baere, T ;
Roche, A ;
Ducreux, M ;
Leclere, J ;
Lasser, P .
BRITISH JOURNAL OF SURGERY, 1999, 86 (06) :784-788
[2]   DETERMINATION OF LIVER VOLUME FROM CT SCANS USING HISTOGRAM CLUSTER-ANALYSIS [J].
FARJO, LA ;
WILLIAMS, DM ;
BLAND, PH ;
FRANCIS, IR ;
MEYER, CR .
JOURNAL OF COMPUTER ASSISTED TOMOGRAPHY, 1992, 16 (05) :674-683
[3]   Proliferative activity of intrahepatic colorectal metastases after preoperative hemihepatic portal vein embolization [J].
Kokudo, N ;
Tada, K ;
Seki, M ;
Ohta, H ;
Azekura, K ;
Ueno, M ;
Ohta, K ;
Yamaguchi, T ;
Matsubara, T ;
Takahashi, T ;
Nakajima, T ;
Muto, T ;
Ikari, T ;
Yanagisawa, A ;
Kato, Y .
HEPATOLOGY, 2001, 34 (02) :267-272
[4]  
Kubota K, 1997, HEPATOLOGY, V26, P1176
[5]  
Nabeshima K, 1998, INT J CANCER, V78, P750, DOI 10.1002/(SICI)1097-0215(19981209)78:6<750::AID-IJC13>3.0.CO
[6]  
2-#
[7]   Immediate increases in arterial blood flow in embolized hepatic segments after portal vein embolization: CT demonstration [J].
Nagino, M ;
Nimura, Y ;
Kamiya, J ;
Kanai, M ;
Hayakawa, N ;
Yamamoto, H .
AMERICAN JOURNAL OF ROENTGENOLOGY, 1998, 171 (04) :1037-1039
[8]   Regeneration of the un-embolized liver parenchyma following portal vein embolization [J].
Yamakado, K ;
Takeda, K ;
Matsumura, K ;
Nakatsuka, A ;
Hirano, T ;
Kato, N ;
Sakuma, H ;
Nakagawa, T ;
Kawarada, Y .
JOURNAL OF HEPATOLOGY, 1997, 27 (05) :871-880
[9]  
YAMANAKA N, 1993, HEPATOLOGY, V18, P79, DOI 10.1016/0270-9139(93)90510-T