Amine- and phosphine-free palladium(II)-catalyzed homocoupling reaction of terminal alkynes

被引：107

作者：

Li, JH ^{[1
]}

Yun, L ^{[1
]}

Zhang, XD ^{[1
]}

机构：

[1] Hunan Normal Univ, Coll Chem & Chem Engn, Key Lab Chem Biol & Tradit Chinese Med Res, Changsha 410081, Peoples R China

来源：

TETRAHEDRON | 2005年 / 61卷 / 07期

基金：

中国国家自然科学基金;

关键词：

phosphine-free; palladium; homecoupling reaction; terminal alkynes;

D O I：

10.1016/j.tet.2004.12.026

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

An efficient, amine- and phosphine-free palladium(II)-catalyzed homocoupling of terminal alkynes has been developed. In the presence of PdCl2, CuI, Me3NO, and NaOAc, homocoupling of various terminal alkynes underwent smoothly to afford the corresponding diynes in moderate to high yields without any phosphine ligands. In contrast, the presence of a phosphine ligand (PPh3) disfavored this palladium-catalyzed homocoupling procedure. Bases, solvents, and CuI have fundamental influence on the palladium-catalyzed homocoupling of terminal alkynes. (C) 2004 Elsevier Ltd. All rights reserved.

引用

页码：1903 / 1907

页数：5

共 36 条

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