Spine fracture prevalence in a nationally representative sample of US women and men aged ≥40 years: results from the National Health and Nutrition Examination Survey (NHANES) 2013-2014

被引:100
作者
Cosman, F. [1 ,2 ]
Krege, J. H. [3 ]
Looker, A. C. [4 ]
Schousboe, J. T. [5 ,6 ]
Fan, B. [7 ]
Isfahani, N. Sarafrazi [4 ]
Shepherd, J. A. [7 ]
Krohn, K. D. [3 ]
Steiger, P. [8 ]
Wilson, K. E. [9 ]
Genant, H. K. [7 ]
机构
[1] Helen Hayes Hosp, Reg Bone Ctr, Route 9W, W Haverstraw, NY 10993 USA
[2] Columbia Univ Coll Phys & Surg, Dept Med, New York, NY 10032 USA
[3] Eli Lilly & Co, Indianapolis, IN 46285 USA
[4] Ctr Dis Control & Prevent, Natl Ctr Hlth Stat, Hyattsville, MD 20782 USA
[5] HealthPartners, HealthPartners Inst, Minneapolis, MN USA
[6] HealthPartners, Pk Nicollet Clin, Minneapolis, MN USA
[7] Univ Calif San Francisco, Dept Radiol, San Francisco, CA USA
[8] Parexel Int, Waltham, MA USA
[9] Hologic Inc, Marlborough, MA USA
关键词
Osteoporosis; Prevalence; Screening; Spine fracture; Vertebral Fracture Assessment (VFA); X-RAY ABSORPTIOMETRY; VERTEBRAL FRACTURE; HIP FRACTURE; POSTMENOPAUSAL WOMEN; UNITED-STATES; ASSESSMENT VFA; RISK-FACTORS; BACK-PAIN; OSTEOPOROSIS; DEFORMITIES;
D O I
10.1007/s00198-017-3948-9
中图分类号
R5 [内科学];
学科分类号
100201 [内科学];
摘要
Spine fracture prevalence is similar in men and women, increasing from < 5 % in those < 60 to 11 % in those 70-79 and 18 % in those ae<yen>80 years. Prevalence was higher with age, lower bone mineral density (BMD), and in those meeting criteria for spine imaging. Most subjects with spine fractures were unaware of them. Spine fractures have substantial medical significance but are seldom recognized. This study collected contemporary nationally representative spine fracture prevalence data. Cross-sectional analysis of 3330 US adults aged >= 40 years participating in NHANES 2013-2014 with evaluable Vertebral Fracture Assessment (VFA). VFA was graded by semiquantitative measurement. BMD and an osteoporosis questionnaire were collected. Overall spine fracture prevalence was 5.4 % and similar in men and women. Prevalence increased with age from < 5 % in those < 60 to 11 % in those 70-79 and 18 % in those ae<yen>80 years. Fractures were more common in non-Hispanic whites and in people with lower body mass index and BMD. Among subjects with spine fracture, 26 % met BMD criteria for osteoporosis. Prevalence was higher in subjects who met National Osteoporosis Foundation (NOF) criteria for spine imaging (14 vs 4.7 %, P < 0.001). Only 8 % of people with a spine fracture diagnosed by VFA had a self-reported fracture, and among those who self-reported a spine fracture, only 21 % were diagnosed with fracture by VFA. Spine fracture prevalence is similar in women and men and increases with age and lower BMD, although most subjects with spine fracture do not meet BMD criteria for osteoporosis. Since most (> 90 %) individuals were unaware of their spine fractures, lateral spine imaging is needed to identify these women and men. Spine fracture prevalence was threefold higher in individuals meeting NOF criteria for spine imaging (similar to 1 in 7 undergoing VFA). Identifying spine fractures as part of comprehensive risk assessment may improve clinical decision making.
引用
收藏
页码:1857 / 1866
页数:10
相关论文
共 50 条
[1]
[Anonymous], 2004, BON HLTH OST REP SUR
[2]
[Anonymous], 2013, VITAL HLTH STAT SERI
[3]
Prevalent vertebral deformities predict hip fractures and new vertebral deformities but not wrist fractures [J].
Black, DM ;
Arden, NK ;
Palermo, L ;
Pearson, J ;
Cummings, SR .
JOURNAL OF BONE AND MINERAL RESEARCH, 1999, 14 (05) :821-828
[4]
Incidence and Mortality of Hip Fractures in the United States [J].
Brauer, Carmen A. ;
Coca-Perraillon, Marcelo ;
Cutler, David M. ;
Rosen, Allison B. .
JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION, 2009, 302 (14) :1573-1579
[5]
Incidence and economic burden of osteoporosis-related fractures in the United States, 2005-2025 [J].
Burge, Russel ;
Dawson-Hughes, Bess ;
Solomon, Daniel H. ;
Wong, John B. ;
King, Alison ;
Tosteson, Anna .
JOURNAL OF BONE AND MINERAL RESEARCH, 2007, 22 (03) :465-475
[6]
Centers for Disease Control and Prevention National Center for Health Statistics, 2013, 2013 2014 DAT DOC CO
[7]
Clinician's Guide to Prevention and Treatment of Osteoporosis [J].
Cosman, F. ;
de Beur, S. J. ;
LeBoff, M. S. ;
Lewiecki, E. M. ;
Tanner, B. ;
Randall, S. ;
Lindsay, R. .
OSTEOPOROSIS INTERNATIONAL, 2014, 25 (10) :2359-2381
[8]
Diagnosis of vertebral fractures by vertebral fracture assessment [J].
Damiano, Joel ;
Kolta, Sami ;
Porcher, Raphael ;
Tournoux, Caroline ;
Dougados, Maxime ;
Roux, Christian .
JOURNAL OF CLINICAL DENSITOMETRY, 2006, 9 (01) :66-71
[9]
Prevalence and severity of vertebral fracture: The Saunders County Bone Quality Study [J].
Davies, KM ;
Stegman, MR ;
Heaney, RP ;
Recker, RR .
OSTEOPOROSIS INTERNATIONAL, 1996, 6 (02) :160-165
[10]
Vertebral Fracture Assessment by Dual X-Ray Absorptiometry: A Valid Tool to Detect Vertebral Fractures in Community-Dwelling Older Adults in a Population-Based Survey [J].
Domiciano, Diogo S. ;
Figueiredo, Camille P. ;
Lopes, Jaqueline B. ;
Kuroishi, Marcia E. ;
Takayama, Liliam ;
Caparbo, Valeria F. ;
Fuller, Priscila ;
Menezes, Paulo F. ;
Scazufca, Marcia ;
Bonfa, Eloisa ;
Pereira, Rosa M. R. .
ARTHRITIS CARE & RESEARCH, 2013, 65 (05) :809-815