Cytogenetic analysis of early nonviable pregnancies after assisted reproduction treatment

被引:70
作者
Carmen Martinez, M. [1 ]
Mendez, Carmen [1 ]
Ferro, Jaime [2 ]
Nicolas, Maria [1 ]
Serra, Vicente [2 ]
Landeras, Jose [1 ]
机构
[1] IVI Murcia, Murcia 30007, Spain
[2] Inst Valenciano Infertilidad, Valencia, Spain
关键词
IN-VITRO FERTILIZATION; INTRACYTOPLASMIC SPERM INJECTION; PREIMPLANTATION GENETIC DIAGNOSIS; SPONTANEOUS-ABORTIONS; CHROMOSOME-ABNORMALITIES; ICSI; ANEUPLOIDY; EMBRYOS; IVF; AGE;
D O I
10.1016/j.fertnstert.2009.07.989
中图分类号
R71 [妇产科学];
学科分类号
100211 ;
摘要
In our series, a very high prevalence of chromosomal abnormalities was observed in spontaneous miscarriages, irrespective of how pregnancy was achieved, by assisted reproductive technology (ART) or natural conception. This high prevalence was equally represented in both groups, with no statistical difference in type of chromosomal abnormalities or in total frequency; however, the incidence of monosomy X is increased and the polyploidies are decreased in abortus after intracytoplasmic sperm injection (ICSI) when it is compared with miscarriages after spontaneous gestations. (Fertil Steril(R) 20 10;93:289-92. (C)2010 by American Society for Reproductive Medicine.)
引用
收藏
页码:289 / 292
页数:4
相关论文
共 38 条
[1]  
Alberman E., 1992, Spontaneous Abortion, P9
[2]   Obstetric outcome of pregnancies after the transfer of cryopreserved and fresh embryos obtained by conventional in-vitro fertilization and intracytoplasmic sperm injection [J].
Aytoz, A ;
Van den Abbeel, E ;
Bonduelle, M ;
Camus, M ;
Joris, H ;
Van Steirteghem, A ;
Devroey, P .
HUMAN REPRODUCTION, 1999, 14 (10) :2619-2624
[3]   THE INFLUENCE OF THE NUMBER OF EMBRYOS TRANSFERRED IN 1060 IN-VITRO FERTILIZATION PREGNANCIES ON MISCARRIAGE RATES AND PREGNANCY OUTCOME [J].
BALEN, AH ;
MACDOUGALL, J ;
TAN, SL .
HUMAN REPRODUCTION, 1993, 8 (08) :1324-1328
[4]  
BARCH MJ, 1997, AGT CYTOGENETICS LAB, P187
[5]   Chromosomal Abnormalities in Miscarriages after Different Assisted Reproduction Procedures [J].
Bettio, D. ;
Venci, A. ;
Setti, P. E. Levi .
PLACENTA, 2008, 29 :S126-S128
[6]   Prenatal testing in ICSI pregnancies: incidence of chromosomal anomalies in 1586 karyotypes and relation to sperm parameters [J].
Bonduelle, M ;
Van Assche, E ;
Joris, H ;
Keymolen, K ;
Devroey, P ;
Van Steirteghem, A ;
Liebaers, I .
HUMAN REPRODUCTION, 2002, 17 (10) :2600-2614
[7]   RETROSPECTIVE AND PROSPECTIVE EPIDEMIOLOGICAL-STUDIES OF 1500 KARYOTYPED SPONTANEOUS HUMAN ABORTIONS [J].
BOUE, J ;
BOUE, A ;
LAZAR, P .
TERATOLOGY, 1975, 12 (01) :11-26
[8]   ART in recurrent miscarriage: preimplantation genetic diagnosis/screening or surrogacy? [J].
Carp, HJA ;
Dirnfeld, M ;
Dor, J ;
Grudzinskas, JG .
HUMAN REPRODUCTION, 2004, 19 (07) :1502-1505
[9]   Chromosome analysis of spontaneous abortions after in vitro fertilization (IVF) and intracytoplasmic sperm injection (ICSI) [J].
Causio, F ;
Fischetto, R ;
Sarcina, E ;
Geusa, S ;
Tartagni, M .
EUROPEAN JOURNAL OF OBSTETRICS & GYNECOLOGY AND REPRODUCTIVE BIOLOGY, 2002, 105 (01) :44-48
[10]   Multicentre trial of preimplantation genetic screening reported in the New England Journal of Medicine:: an in-depth look at the findings [J].
Cohen, Jacques ;
Grifo, James A. .
REPRODUCTIVE BIOMEDICINE ONLINE, 2007, 15 (04) :365-366