Synthesis and in vitro photodynamic activity of new hexadeca-carboxy phthalocyanines

被引：61

作者：

Choi, CF

Tsang, PT

Huang, JD

Chan, EYM

Ko, WH

Fong, WP ^{[1
]}

Ng, DKP

机构：

[1] Chinese Univ Hong Kong, Dept Biochem, Shatin, Hong Kong, Peoples R China

[2] Chinese Univ Hong Kong, Dept Chem, Shatin, Hong Kong, Peoples R China

[3] Chinese Univ Hong Kong, Dept Physiol, Shatin, Hong Kong, Peoples R China

来源：

CHEMICAL COMMUNICATIONS | 2004年 / 19期

关键词：

D O I：

10.1039/b405868b

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

Two new hexadeca-carboxy phthalocyanines have been synthesised and evaluated for their photodynamic activities; the zinc(II) analogue exhibits a high class-A scavenger-receptor mediated photocytotoxicity towards the J774 murine macrophage cell line.

引用

页码：2236 / 2237

页数：2

共 19 条

[1] Metal complexes as photo- and radiosensitizers [J].

Ali, H ;

van Lier, JE .

CHEMICAL REVIEWS, 1999, 99 (09) :2379-2450

[2]

de Vries HE, 1999, J PHARMACOL EXP THER, V289, P528

[3] Photodynamic therapy for cancer [J].

Dolmans, DEJGJ ;

Fukumura, D ;

Jain, RK .

NATURE REVIEWS CANCER, 2003, 3 (05) :380-387

[4]

Hamblin MR, 2000, PHOTOCHEM PHOTOBIOL, V72, P533, DOI 10.1562/0031-8655(2000)072<0533:SRTPT>2.0.CO

[5]

[6] Halogenated silicon(IV) phthalocyanines with axial poly(ethylene glycol) chains.: Synthesis, spectroscopic properties, complexation with bovine serum albumin and in vitro photodynamic activities [J].

Huang, JD ;

Wang, SQ ;

Lo, PC ;

Fong, WP ;

Ko, WH ;

Ng, DKP .

NEW JOURNAL OF CHEMISTRY, 2004, 28 (03) :348-354

[7] FAR-RED-ABSORBING PHOTOSENSITIZERS - THEIR USE IN THE PHOTODYNAMIC THERAPY OF TUMORS [J].

JORI, G .

JOURNAL OF PHOTOCHEMISTRY AND PHOTOBIOLOGY A-CHEMISTRY, 1992, 62 (03) :371-378

[8] IRON(III) PHTHALOCYANINES - OXIDATION AND SPIN STATES OF IRON IN IRON PHTHALOCYANINES WITH CARBOXYL GROUPS [J].

KOBAYASHI, N ;

SHIRAI, H ;

HOJO, N .

JOURNAL OF THE CHEMICAL SOCIETY-DALTON TRANSACTIONS, 1984, (10) :2107-2110

[9] Influence of surfactants on the aggregation behavior of water-soluble dendritic phthalocyanines [J].

Li, XY ;

He, X ;

Ng, ACH ;

Wu, C ;

Ng, DKP .

MACROMOLECULES, 2000, 33 (06) :2119-2123

[10]

LO PC, IN PRESS CHEM EUR J

← 1 2 →