Synthesis and biological activity of artificial analogs of mycalamide A

被引：31

作者：

Fukui, H

Tsuchiya, Y

Fujita, K

Nakagawa, T

Koshino, H

Nakata, T

机构：

[1] KAKEN PHARMACEUT CO LTD,CENT RES INST,KYOTO 607,JAPAN

[2] INST PHYS & CHEM RES,WAKO,SAITAMA 35101,JAPAN

来源：

BIOORGANIC & MEDICINAL CHEMISTRY LETTERS | 1997年 / 7卷 / 16期

关键词：

D O I：

10.1016/S0960-894X(97)00365-X

中图分类号：

R914 [药物化学];

学科分类号：

100701 ;

摘要：

Artificial analogs of mycalamide A, a potent antitumor and antiviral compound isolated from a New Zealand marine sponge, were synthesized and their biological activities were tested. (C) 1997 Published by Elsevier Science Ltd.

引用

页码：2081 / 2086

页数：6

共 30 条

[1]

BURRES NS, 1989, CANCER RES, V49, P2935

[2]

CARDANI C, 1965, TETRAHEDRON LETT, P2537

[3]

DAVIS J, 1994, POL J CHEM, V68, P2249

[4]

FURUSAKI A, 1968, TETRAHEDRON LETT, P6301

[5] BIOACTIVE MARINE METABOLITES SERIES .41. THEOPEDERINS-A-E, POTENT ANTITUMOR METABOLITES FROM A MARINE SPONGE, THEONELLA SP [J].

FUSETANI, N ;

SUGAWARA, T ;

MATSUNAGA, S .

JOURNAL OF ORGANIC CHEMISTRY, 1992, 57 (14) :3828-3832

[6] EFFECTS OF CYCLOSPORINE-A, FK-506, AND MYCALAMIDE-A ON THE ACTIVATION OF MURINE-CD4+ T-CELLS BY THE MURINE B7-ANTIGEN [J].

GALVIN, F ;

FREEMAN, GJ ;

RAZIWOLF, Z ;

BENACERRAF, B ;

NADLER, L ;

REISER, H .

EUROPEAN JOURNAL OF IMMUNOLOGY, 1993, 23 (01) :283-286

[7] SYNTHESIS OF THE TRIOXADECALIN-PART OF MYCALAMIDE-B [J].

HOFFMANN, RW ;

SCHLAPBACH, A .

TETRAHEDRON LETTERS, 1993, 34 (49) :7903-7906

[8] Model studies towards a novel fragment coupling for the synthesis of mycalamides and related natural products [J].

Hoffmann, RW ;

Breitfelder, S ;

Schlapbach, A .

HELVETICA CHIMICA ACTA, 1996, 79 (02) :346-352

[9] TOTAL SYNTHESIS OF ONNAMIDE-A [J].

HONG, CY ;

KISHI, Y .

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 1991, 113 (25) :9693-9694

[10] TOTAL SYNTHESIS OF MYCALAMIDE-A AND MYCALAMIDE-B [J].

HONG, CY ;

KISHI, Y .

JOURNAL OF ORGANIC CHEMISTRY, 1990, 55 (14) :4242-4245

← 1 2 3 →