R/qtl: QTL mapping in experimental crosses

被引：2728

作者：

Broman, KW

Wu, H

Sen, S

Churchill, GA

机构：

[1] Johns Hopkins Univ, Dept Biostat, Baltimore, MD 21205 USA

[2] Jackson Lab, Bar Harbor, ME 04609 USA

来源：

BIOINFORMATICS | 2003年 / 19卷 / 07期

关键词：

D O I：

10.1093/bioinformatics/btg112

中图分类号：

Q5 [生物化学];

学科分类号：

071010 [生物化学与分子生物学]; 081704 [应用化学];

摘要：

R/qtl is an extensible, interactive environment for mapping quantitative trait loci (QTLs) in experimental populations derived from inbred lines. It is implemented as an add-on package for the freely-available statistical software, R, and includes functions for estimating genetic maps, identifying genotyping errors, and performing single-QTL and two-dimensional, two-QTL genome scans by multiple methods, with the possible inclusion of covariates.

引用

页码：889 / 890

页数：2

共 11 条

[1]

A MAXIMIZATION TECHNIQUE OCCURRING IN STATISTICAL ANALYSIS OF PROBABILISTIC FUNCTIONS OF MARKOV CHAINS [J].