Heterocycle synthesis by copper facilitated addition of heteroatoms to alkenes, alkynes and arenes

被引:299
作者
Chemler, Sherry R. [1 ]
Fuller, Peter H. [1 ]
机构
[1] SUNY Buffalo, Dept Chem, Buffalo, NY 14260 USA
关键词
D O I
10.1039/b607819m
中图分类号
O6 [化学];
学科分类号
0703 ;
摘要
The de nouvo synthesis of small organic heterocyclic molecules has benefited from recent protocols for copper-facilitated additions of heteroatoms to alkenes, alkynes and arenes. This tutorial review summarizes a number of these recent contributions. Copper salts can facilitate bond formations due to their ability to serve as Lewis acids, oxidizing agents and transition metal catalysts. The current understanding of the mechanisms of these reactions is presented. This review should be of interest to chemists involved in the synthesis of heterocycles and those investigating transition metal facilitated reactions.
引用
收藏
页码:1153 / 1160
页数:8
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