Support vector machines for prediction of protein domain structural class

被引:39
作者
Cai, YD
Liu, XJ
Xu, XB
Chou, KC
机构
[1] Chinese Acad Sci, Shanghai Res Ctr Biotechnol, Shanghai 200233, Peoples R China
[2] Univ Edinburgh, Inst Cell Anim & Populat Biol, Edinburgh EH9 3JT, Midlothian, Scotland
[3] Univ Wales Coll Cardiff, Dept Comp Sci, Cardiff CF2 3XF, S Glam, Wales
[4] Pfizer, Upjohn Labs, Kalamazoo, MI 49001 USA
关键词
D O I
10.1006/jtbi.2003.3179
中图分类号
Q [生物科学];
学科分类号
07 ; 0710 ; 09 ;
摘要
The support vector machines (SVMs) method was introduced for predicting the structural class of protein domains. The results obtained through the self-consistency test, jack-knife test, and independent dataset test have indicated that the current method and the elegant component-coupled algorithm developed by Chou and co-workers, if effectively complemented with each other, may become a powerful tool for predicting the structural class of protein domains. (C) 2002 Elsevier Science Ltd. All rights reserved.
引用
收藏
页码:115 / 120
页数:6
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