Impact of surgically-induced weight loss on respiratory function:: A prospective analysis

被引:41
作者
Dávila-Cervantes, A
Domínguez-Cherit, G
Borunda, D
Gamino, R
Vargas-Vorackova, F
González-Barranco, J
Herrera, MF
机构
[1] Inst Nacl Ciencias Med & Nutr Salvador Zubiran, Dept Surg, Mexico City 14000, DF, Mexico
[2] Inst Nacl Ciencias Med & Nutr Salvador Zubiran, Dept Crit Care, Mexico City 14000, DF, Mexico
[3] Inst Nacl Ciencias Med & Nutr Salvador Zubiran, Dept Gastroenterol, Mexico City 14000, DF, Mexico
[4] Inst Nacl Ciencias Med & Nutr Salvador Zubiran, Obesity Clin, Mexico City 14000, DF, Mexico
关键词
morbid obesity; vertical banded gastroplasty; pulmonary function in obesity; obstructive apnea syndrome; obesity hypoventilation syndrome;
D O I
10.1381/0960892042583996
中图分类号
R61 [外科手术学];
学科分类号
摘要
Background: Morbid obesity (MO) causes several degrees of respiratory impairment that may resolve after weight reduction. The aims of the present study were to investigate the frequency of respiratory impairment in a selected cohort of morbidly obese patients with BMI 40-50 kg/m(2) with no respiratory symptoms and to evaluate the impact of surgically-induced weight loss on respiratory function. Methods: Prospective analysis of respiratory impairment was conducted before surgery and 1 year after surgery in a cohort of patients with MO who underwent vertical banded gastroplasty (VBG). 30 consecutive patients with MO who underwent VBG (14 open and 16 laparoscopic) in a 1-year period were studied. Respiratory function tests, arterial blood gases and hemoglobin were obtained in all patients before and 1 year after VBG. Results: Results were analyzed using the Wilcoxon signed-rank test and Spearman for variables without normal distribution. Mean age was 35+/-8 years; there were 3 males and 27 females. BMI was 44+/-4 kg/m(2) before surgery and 32 4 kg/m(2) at 1-year follow-up. By respiratory function tests, the diagnosis of obstructive disease was made before surgery in 4 patients and a restrictive disorder was identified in 4 additional patients. Evidence of pulmonary disease was absent in all patients 1 year after surgery. Forced vital capacity, inspiratory and expiratory forces, tidal volume, SaO(2), and PaCO2 significantly improved after weight reduction. Conclusion: Surgically-induced weight loss significantly improves pulmonary function.
引用
收藏
页码:1389 / 1392
页数:4
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