Isolated cardiac cells for electropharmacological studies

被引：15

作者：

Cerbai, E ^{[1
]}

Sartiani, L ^{[1
]}

De Paoli, P ^{[1
]}

Mugelli, A ^{[1
]}

机构：

[1] Univ Florence, Dept Preclin & Clin Pharmacol, I-50139 Florence, Italy

来源：

PHARMACOLOGICAL RESEARCH | 2000年 / 42卷 / 01期

关键词：

isolated myocytes; patch-clamp; ionic currents;

D O I：

10.1006/phrs.1999.0654

中图分类号：

R9 [药学];

学科分类号：

1007 ;

摘要：

Single cardiac myocytes provide a Model widely used to characterize the electrophysiological properties of drugs and to identify new therapeutic targets. This review focuses on isolation procedures to obtain single cardiac myocytes from several mammal species, including humans, and on patch-clamp technique as a useful method to investigate the molecular mechanism of druy actions. (C) 2000 Academic Press.

引用

页码：1 / 8

页数：8

共 63 条

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