Preparation of cyclic alkenylmagnesium reagents via an iodine/magnesium exchange

被引：62

作者：

Ren, HJ ^{[1
]}

Krasovskiy, A ^{[1
]}

Knochel, P ^{[1
]}

机构：

[1] Univ Munich, Dept Chem, D-81377 Munich, Germany

来源：

CHEMICAL COMMUNICATIONS | 2005年 / 04期

关键词：

D O I：

10.1039/b415588b

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

The reaction of various cyclic alkenyl iodides with i-PrMgCl.LiCl produces the corresponding alkenylmagnesium reagents under mild conditions. After reaction with various electrophiles, like allylic halides, disulfides, aldehydes and acid chlorides, the expected products are obtained in 53-91% yield. Remarkably, the mild conditions of the I/Mg-exchange tolerate the presence of sensitive diene functionalities.

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页码：543 / 545

页数：3

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