Aggregative activation in heterocyclic chemistry.: Part 5.: Lithiation of pyridine and quinoline with the complex base BuLi•Me2N(CH2)2OLi (BuLi•LiDMAE)

被引：41

作者：

Gros, P ^{[1
]}

Fort, Y ^{[1
]}

Caubère, P ^{[1
]}

机构：

[1] Univ Henri Poincare Nancy 1, Fac Sci, Lab Chim Organ 1, CNRS,UA 457, F-54506 Vandoeuvre Nancy, France

来源：

JOURNAL OF THE CHEMICAL SOCIETY-PERKIN TRANSACTIONS 1 | 1997年 / 24期

关键词：

D O I：

10.1039/a705027e

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

It is shown that the complex base BuLi.LiDMAE reacts with pyridine to give metallated species which, after trapping by electrophiles, lead to 2-substituted pyridines in good to excellent yields, The same reactions have been less successfully performed with quinoline.

引用

页码：3597 / 3600

页数：4

共 32 条

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