Four new germine esters from Veratrum dahuricum

被引:18
作者
Tang, Jian
Li, Hui-Liang
Shen, Yun-Heng
Jin, Hui-Zi
Yan, Shi-Kai
Liu, Run-Hui
Zhang, Wei-Dong [1 ]
机构
[1] Shanghai Jiao Tong Univ, Sch Pharm, Shanghai 200240, Peoples R China
[2] Mil Med Univ 2, Sch Pharm, Dept Phytochem, Shanghai 200433, Peoples R China
关键词
D O I
10.1002/hlca.200790078
中图分类号
O6 [化学];
学科分类号
0703 [化学];
摘要
Four new alkaloids, compounds 1 - 4, based on the germine (= 4,9-epoxycevane-3,4,7,14,15,16,20-heptol; 5) framework, were isolated from the rhizomes of V dahuricum, together with germine proper. The X-ray crystal structure of germine (5) was solved, and all compounds were characterized by circular dichroism, 1D- and 2D-NMR (H-1,H-1-COSY, DEPT, HSQC, HMBC), as well as HR-MS analyses.
引用
收藏
页码:769 / 775
页数:7
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