In Vivo Evaluation of Novel pH-sensitive mPEG-Hz-Chol Conjugate in Liposomes: Pharmacokinetics, Tissue Distribution, Efficacy Assessment

被引：29

作者：

Chen, Daquan ^{[1
]}

Jiang, Xiaoqun ^{[2
]}

Liu, Jia ^{[1
]}

Jin, Xiang ^{[1
]}

Zhang, Can ^{[1
]}

Ping, Qineng ^{[1
]}

机构：

[1] China Pharmaceut Univ, Coll Pharm, Nanjing 210009, Peoples R China

[2] Nanjing Hicin Pharmaceut Co Ltd, Nanjing, Peoples R China

来源：

ARTIFICIAL CELLS BLOOD SUBSTITUTES AND BIOTECHNOLOGY | 2010年 / 38卷 / 03期

基金：

中国国家自然科学基金;

关键词：

LONG-CIRCULATING LIPOSOME; POLY(ETHYLENE GLYCOL); PACLITAXEL; THERAPY; FORMULATIONS; DELIVERY; AGENTS;

D O I：

10.3109/10731191003685481

中图分类号：

Q81 [生物工程学（生物技术）]; Q93 [微生物学];

学科分类号：

071005 [微生物学]; 090105 [作物生产系统与生态工程];

摘要：

[No abstract available]

引用

页码：136 / 142

页数：7

共 20 条

[1]

Liposomal drug formulations - Rationale for development and what we can expect for the future [J].

Allen, TM .

DRUGS, 1998, 56 (05) :747-756

[2]

Drummond DC, 1999, PHARMACOL REV, V51, P691

[3]

Polyethylene glycol-complexed cationic liposome for enhanced cellular uptake and anticancer activity [J].

Jung, Suk Hyun ;

Jung, Soon Hwa ;

Seong, Hasoo ;

Cho, Sun Hang ;

Jeong, Kyu-Sung ;

Shin, Byung Cheol .

INTERNATIONAL JOURNAL OF PHARMACEUTICS, 2009, 382 (1-2) :254-261

[4]

Long-circulating liposome-encapsulated ganciclovir enhances the efficacy of HSV-TK suicide gene therapy [J].

Kajiwara, Elichi ;

Kawano, Kumi ;

Hattori, Yoshiyuki ;

Fukushima, Masayoshi ;

Hayashi, Kyoko ;

Maitani, Yoshie .

JOURNAL OF CONTROLLED RELEASE, 2007, 120 (1-2) :104-110

[5]

Smart drug carriers: PEGylated TATp-Modified pH-Sensitive Liposomes [J].

Kale, Amit A. ;

Torchilin, Vladimir P. .

JOURNAL OF LIPOSOME RESEARCH, 2007, 17 (3-4) :197-203

[6]

NOVEL PH-SENSITIVE LIPOSOMES - LIPOSOMES BEARING A POLY(ETHYLENE GLYCOL) DERIVATIVE WITH CARBOXYL GROUPS [J].

KONO, K ;

ZENITANI, K ;

TAKAGISHI, T .

BIOCHIMICA ET BIOPHYSICA ACTA-BIOMEMBRANES, 1994, 1193 (01) :1-9

[7]

Anti-neovascular therapy by use of tumor neovasculature-targeted long-circulating liposome [J].

Maeda, N ;

Takeuchi, Y ;

Takada, M ;

Sadzuka, Y ;

Namba, Y ;

Oku, N .

JOURNAL OF CONTROLLED RELEASE, 2004, 100 (01) :41-52

[8]

Targeting Stealth liposomes in a murine model of human small cell lung cancer [J].

Moreira, JN ;

Gaspar, R ;

Allen, TM .

BIOCHIMICA ET BIOPHYSICA ACTA-BIOMEMBRANES, 2001, 1515 (02) :167-176

[9]

Pharmaceutical aspects of paclitaxel [J].

Panchagnula, R .

INTERNATIONAL JOURNAL OF PHARMACEUTICS, 1998, 172 (1-2) :1-15

[10]

DRUG-THERAPY - PACLITAXEL (TAXOL) [J].

ROWINSKY, EK ;

DONEHOWER, RC .

NEW ENGLAND JOURNAL OF MEDICINE, 1995, 332 (15) :1004-1014

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