SilicaROD™ -: A new challenge in fast high-performance liquid chromatography separations

被引：112

作者：

Cabrera, K

Wieland, G

Lubda, D

Nakanishi, K

Soga, N

Minakuchi, H

Unger, KK

机构：

[1] Merck KGaA, Dept R&D Chromatog, D-64271 Darmstadt, Germany

[2] Kyoto Univ, Grad Sch Engn, Dept Chem Mat, Sakyo Ku, Kyoto 60601, Japan

[3] Univ Mainz, Inst Anorgan Chem & Analyt Chem, D-55099 Mainz, Germany

来源：

TRAC-TRENDS IN ANALYTICAL CHEMISTRY | 1998年 / 17卷 / 01期

关键词：

fast HPLC separation; monolithic porous silica rods; continuous monolithic porous silica column; SilicaROD (TM) column; flow rate gradient;

D O I：

10.1016/S0165-9936(97)00091-5

中图分类号：

O65 [分析化学];

学科分类号：

070302 ; 081704 ;

摘要：

High performance liquid chromatography (HPLC) has become one of the most used methods for the analysis of compound mixtures in industry, especially for the quality control of products, Nowadays productivity is the major and dominant upcoming issue, i.e. the goal is to drastically reduce the analysis time and cost per analysis, The solution of the task is higher throughput and faster HPLC methods, Here we describe a new monolithic type of HPLC column, the SilicaROD(TM) column, which permits the fast HPLC separation of compound mixtures within a few minutes. (C) 1998 Elsevier Science B.V.

引用

页码：50 / 53

页数：4

共 11 条

[1]

CABRERA K, 1996, NACHR CHEM TECH LAB, V44

[2] THE INFLUENCE OF SILICA STRUCTURE ON REVERSED-PHASE RETENTION [J].