Prolonged dexmedetomidine infusion as an adjunct in treating sedation-induced withdrawal

被引:39
作者
Multz, AS [1 ]
机构
[1] Long Isl Jewish Med Ctr, Med ICU, New Hyde Pk, NY 11040 USA
关键词
D O I
10.1213/01.ANE.0000050773.70232.08
中图分类号
R614 [麻醉学];
学科分类号
100217 ;
摘要
Dexmedetomidine, an α2-adrenoceptor agonist, is indicated for sedating patients on mechanical ventilation. It has been approved by the Food and Drug Administration for 24-h use. This is a report concerning a patient in whom a continuous infusion of dexmedetomidine was safely used for a week to help in averting frank withdrawal symptoms from an opioid and benzodiazepines.
引用
收藏
页码:1054 / 1055
页数:2
相关论文
共 19 条
[1]  
Aley KO, 1997, J NEUROSCI, V17, P3907
[2]  
ASHTON H, 1987, BRIT J ADDICT, V82, P665
[3]  
COUPAR IM, 1992, N-S ARCH PHARMACOL, V345, P553
[4]   EFFECTS OF CLONIDINE ON NARCOTIC REQUIREMENTS AND HEMODYNAMIC-RESPONSE DURING INDUCTION OF FENTANYL ANESTHESIA AND ENDOTRACHEAL INTUBATION [J].
GHIGNONE, M ;
QUINTIN, L ;
DUKE, PC ;
KEHLER, CH ;
CALVILLO, O .
ANESTHESIOLOGY, 1986, 64 (01) :36-42
[5]   α2A-adrenergic receptors are present in μ-opioid receptor containing neurons in rat medial nucleus tractus solitarius [J].
Glass, MJ ;
Pickel, VM .
SYNAPSE, 2002, 43 (03) :208-218
[6]   Sedative, amnestic, and analgesic properties of small-dose dexmedetomidine infusions [J].
Hall, JE ;
Uhrich, TD ;
Barney, JA ;
Arain, SR ;
Ebert, TJ .
ANESTHESIA AND ANALGESIA, 2000, 90 (03) :699-705
[7]   Clinical practice guidelines for the sustained use of sedatives and analgesics in the critically ill adult [J].
Jacobi, J ;
Fraser, GL ;
Coursin, DB ;
Riker, RR ;
Fontaine, D ;
Wittbrodt, ET ;
Chalfin, DB ;
Masica, MF ;
Bjerke, HS ;
Coplin, WM ;
Crippen, DW ;
Fuchs, BD ;
Kelleher, RM ;
Marik, PE ;
Nasraway, SA ;
Murray, MJ ;
Peruzzi, WT ;
Lumb, PD .
CRITICAL CARE MEDICINE, 2002, 30 (01) :119-141
[8]   DEXMEDETOMIDINE PARTIALLY ATTENUATES THE SYMPATHETICALLY MEDIATED SYSTEMIC AND CORONARY HEMODYNAMIC-EFFECTS OF COCAINE [J].
KERSTEN, JR ;
PAGEL, PS ;
HETTRICK, DA ;
WARLTIER, DC .
ANESTHESIA AND ANALGESIA, 1995, 80 (01) :114-121
[9]   Alpha-2 and imidazoline receptor agonists - Their pharmacology and therapeutic role [J].
Khan, ZP ;
Ferguson, CN ;
Jones, RM .
ANAESTHESIA, 1999, 54 (02) :146-165
[10]   EFFECT OF LESIONS OF ASCENDING NORADRENALINE PATHWAYS ON SLEEP AND WAKING IN RAT [J].
LIDBRINK, P .
BRAIN RESEARCH, 1974, 74 (01) :19-40