Cytochrome P450 enzyme systems in fungi

被引：167

作者：

van den Brink, HJM ^{[1
]}

van Gorcom, RFM ^{[1
]}

van den Hondel, CAMJJ ^{[1
]}

Punt, PJ ^{[1
]}

机构：

[1] TNO, Nutr & Food Res Inst, Dept Mol Genet & Gene Technol, NL-3700 AJ Zeist, Netherlands

来源：

FUNGAL GENETICS AND BIOLOGY | 1998年 / 23卷 / 01期

关键词：

cytochrome P450; CYP; CPR; bioconversion; biotransformation;

D O I：

10.1006/fgbi.1997.1021

中图分类号：

Q3 [遗传学];

学科分类号：

071007 ; 090102 ;

摘要：

The involvement of cytochrome P450 enzymes in many complex fungal bioconversion processes has been characterized in recent years, Accordingly, there is now considerable scientific interest in fungal cytochrome P450 enzyme systems, In contrast to S. cerevisiae, where surprisingly few P450 genes have been identified, biochemical data suggest that many fungi posses numerous P450 genes, This review summarizes the current information pertaining to these fungal cytochrome P450 systems, with emphasis on the molecular genetics, The use of molecular techniques to improve cytochrome P450 activities in fungi is also discussed. (C) 1998 Academic Press.

引用

页码：1 / 17

页数：17

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