Preinjury warfarin and geriatric orthopedic trauma patients: A case-matched study

Background: This study examined the hypothesis that patients on warfarin before sustaining orthopedic injuries will have increased morbidity and mortality compared with matched control patients not on warfarin. Methods: Records of consecutive trauma patients on warfarin with orthopedic fractures who presented from January 1997 to June 2002 to a Level I trauma center were retrospectively analyzed. Data were evaluated using the chi(2) and Student's t tests and nonparametric tests when appropriate; values of p < 0.05 were considered significant. Results: A study group of 53 patients was available for review. In comparison with the control group, significant differences were found in time delay from admission to surgery (p = 0.005), hospital length of stay (p = 0.03), total units of blood transfused (p = 0.03), and discharge disposition (p < 0.0003). No difference was found in number of intensive care unit days, complications, or mortality. Conclusion: Preinjury warfarin impacts outcomes of geriatric trauma patients sustaining orthopedic injuries.