Hippocampal sclerosis is a progressive disorder: A longitudinal volumetric MRI study

被引：178

作者：

Fuerst, D ^{[1
]}

Shah, J ^{[1
]}

Shah, A ^{[1
]}

Watson, C ^{[1
]}

机构：

[1] Wayne State Univ, Sch Med, Dept Neurol, Detroit, MI 48201 USA

来源：

ANNALS OF NEUROLOGY | 2003年 / 53卷 / 03期

关键词：

D O I：

10.1002/ana.10509

中图分类号：

R74 [神经病学与精神病学];

学科分类号：

摘要：

Twelve patients with refractory temporal lobe epilepsy and unilateral hippocampal sclerosis had repeat volumetric magnetic resonance imaging scans after a mean of 3.4 years to determine whether progressive hippocampal volume loss occurred. Seizure-free patients showed no change in hippocampal volume. Patients with continuing seizures had a decline in ipsilateral hippocampal volume that correlated with seizure frequency. Patients with medically refractory temporal lobe epilepsy and unilateral hippocampal sclerosis have progressive hippocampal atrophy.

引用

页码：413 / 416

页数：4

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