Studies of zoanthamine alkaloids. Enantiocontrolled construction of the tetracyclic hemi-aminal core.

被引：45

作者：

Williams, DR ^{[1
]}

Cortez, GS ^{[1
]}

机构：

[1] Indiana Univ, Dept Chem, Bloomington, IN 47405 USA

来源：

TETRAHEDRON LETTERS | 1998年 / 39卷 / 18期

基金：

美国国家卫生研究院;

关键词：

D O I：

10.1016/S0040-4039(98)00369-4

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

A concise enantiocontrolled synthesis of the enamine-aminal heterocyclic core found in the zoanthamine alkaloids is presented. Conjugate addition of a chiral imine provides for excellent diastereofacial selectivity in the generation of the quaternary C-9 asymmetry, of 4. (C) 1998 Elsevier Science Ltd. All rights reserved.

引用

页码：2675 / 2678

页数：4

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