Sustained molecular remission after low dose gemtuzumab-ozogamicin in elderly patients with advanced acute promyelocytic leukemia

被引:34
作者
Breccia, Massimo [1 ]
Cimino, Giuseppe [1 ]
Diverio, Daniela [1 ]
Gentilini, Fabiana [1 ]
Mandelli, Franco [1 ]
Lo Coco, Francesco [2 ]
机构
[1] Univ Roma La Sapienza, Dept Cellular Biotechnol & Hematol, Rome, Italy
[2] Univ Tor Vergata, Dept Biopathol, Rome, Italy
关键词
acute promyelocytic leukemia; gentuzumab ozogamicin; molecular relapse;
D O I
10.3324/haematol.11329
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
We report here a preliminary experience with gemtuzumab ozogamicin (GO) used at low dosage (3 mg/m(2)) in 3 elderly patients with acute promyelocytic leukaemia (APL) who presented molecular relapse and were unfit for intensive chemotherapy.
引用
收藏
页码:1273 / 1274
页数:2
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