Pigmented choroid plexus carcinoma: A cytogenetic and ultrastructural study

被引：6

作者：

Dobin, SM ^{[1
]}

Donner, LR ^{[1
]}

机构：

[1] TEXAS A&M UNIV, CTR HLTH SCI,COLL MED,SHERWOOD & BRINDLEY FDN, SCOTT & WHITE MEM HOSP & CLIN, TEMPLE, TX 76508 USA

来源：

CANCER GENETICS AND CYTOGENETICS | 1997年 / 96卷 / 01期

关键词：

D O I：

10.1016/S0165-4608(96)00264-6

中图分类号：

R73 [肿瘤学];

学科分类号：

100214 ;

摘要：

A pigmented choroid plexus carcinoma was studied. The pigment was Fontana-positive, and the neoplastic cells focally expressed melanosomal marker HMB45 and contained probable aberrant melanosomes. The tumor was composed of two pseudodiploid clones, having the karyotypes 46,Xu,inv(4)(q12q35),t(6;15)(q21;q22),inv(7)(p11.2q22),t(19;22)(q13.4;q11.2)[15]/46,XY,t(4;14)(q31.1; p11.2),t(12;13)(p11.2;q34)[6]. The available data seem to indicate that rearrangements of 7p11-12, 9q11-12, 15q22, and 19q13.4 may play a role in the development of choroid plexus carcinomas. (C) Elsevier Science Inc., 1997.

引用

页码：37 / 41

页数：5

共 21 条

[1] CHROMOSOMAL-ABNORMALITIES IN 47 PEDIATRIC BRAIN-TUMORS [J].