Microbiology and drug resistance mechanisms of fully resistant pathogens

被引:117
作者
Walsh, FM
Amyes, SGB
机构
[1] Univ Edinburgh, Sch Med, Sch Biomed, Edinburgh EH8 9AG, Midlothian, Scotland
[2] Univ Edinburgh, Sch Med, Clin Sci Lab, Edinburgh EH8 9AG, Midlothian, Scotland
关键词
D O I
10.1016/j.mib.2004.08.007
中图分类号
Q93 [微生物学];
学科分类号
071005 ; 100705 ;
摘要
The acquisition of vancomycin resistance by Gram-positive bacteria and carbapenem resistance by Gram-negative bacteria has rendered some hospital-acquired pathogens impossible to treat. The resistance mechanisms employed are sophisticated and very difficult to overcome. Unless alternative treatment regimes are initiated soon, our inability to treat totally resistant bacteria will halt other developments in medicine. In the community, Gram-positive bacteria responsible for pneumonia could become totally resistant leading to increased mortality from this common infection, which would have a more immediate impact on our current lifestyles.
引用
收藏
页码:439 / 444
页数:6
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