Antibiotic resistance patterns of mecA-positive Staphylococcus aureus isolates from clinical specimens and nasal carriage

被引：27

作者：

Al-Zu'Bi, E

Bdour, S ^{[1
]}

Shehabi, AA

机构：

[1] Univ Jordan, Fac Sci, Dept Biol Sci, Amman, Jordan

[2] Univ Jordan, Fac Med, Dept Pathol Microbiol, Amman, Jordan

来源：

MICROBIAL DRUG RESISTANCE | 2004年 / 10卷 / 04期

关键词：

D O I：

10.1089/mdr.2004.10.321

中图分类号：

R51 [传染病];

学科分类号：

100401 ;

摘要：

The present study demonstrates that the nasal carriage rate of Staphylococcus aureus was 40% in Jordanian healthy young adult population, and 19% of nasal S. aureus and 57% of clinical isolates over the same period were resistant to oxacillin (MRSA), respectively. The mecA gene was detected in all MRSA isolates in both groups. Most of MRSA isolates were multiresistant to three antibiotic classes (beta-lactams, aminoglycosides, macrolides-lincosamides). This result suggests a serious problem may be encountered in treatment of staphylococcal infections in Jordan.

引用

收藏

页码：321 / 324

页数：4

相关论文

共 19 条

[1] Methicillin-resistant Staphylococcus aureus (MRSA):: a community-based prevalence survey [J].

Abudu, L ;

Blair, I ;

Fraise, A ;

Cheng, KK .

EPIDEMIOLOGY AND INFECTION, 2001, 126 (03) :351-356

[2] Nasal carriage and antibiotic resistance of Staphylococcus aureus isolates from hospital and non-hospital personnel in Abha, Saudi Arabia [J].

Alghaithy, AA ;

Bilal, NE ;

Gedebou, M ;

Weily, AH .

TRANSACTIONS OF THE ROYAL SOCIETY OF TROPICAL MEDICINE AND HYGIENE, 2000, 94 (05) :504-507

[3]

ARAJ GF, 2000, LEBAN MED J, V48, P221

[4] Emergence of methicillin-resistant Staphylococcus aureus as a community pathogen [J].

Bukharie, HA ;

Abdelhadi, MS ;

Saeed, IA ;

Rubaish, AM ;

Larbi, EB .

DIAGNOSTIC MICROBIOLOGY AND INFECTIOUS DISEASE, 2001, 40 (1-2) :1-4

[5] Methicillin resistance in staphylococci: Molecular and biochemical basis and clinical implications [J].

Chambers, HF .

CLINICAL MICROBIOLOGY REVIEWS, 1997, 10 (04) :781-+

[6] Frequency of nasal and wound isolates of Staphylococcus aureus associated with TSST-1 production in Jordanian population [J].

Daghistani, HI ;

Issa, AA ;

Shehabi, AA .

FEMS IMMUNOLOGY AND MEDICAL MICROBIOLOGY, 2000, 27 (02) :95-98

[7] Survey of infections due to Staphylococcus species:: Frequency of occurrence and antimicrobial susceptibility of isolates collected in the United States, Canada, Latin America, Europe, and the Western Pacific region for the SENTRY Antimicrobial Surveillance Program, 1997-1999 [J].

Diekema, DJ ;

Pfaller, MA ;

Schmitz, FJ ;

Smayevsky, J ;

Bell, J ;

Jones, RN ;

Beach, M .

CLINICAL INFECTIOUS DISEASES, 2001, 32 :S114-S132

[8] MULTIPLEX PCR FOR IDENTIFICATION OF METHICILLIN-RESISTANT STAPHYLOCOCCI IN THE CLINICAL LABORATORY [J].

GEHA, DJ ;

UHL, JR ;

GUSTAFERRO, CA ;

PERSING, DH .

JOURNAL OF CLINICAL MICROBIOLOGY, 1994, 32 (07) :1768-1772

[9] COMPARISON OF CONVENTIONAL SUSCEPTIBILITY TESTS WITH DIRECT DETECTION OF PENICILLIN-BINDING PROTEIN-2A IN BORDERLINE OXACILLIN-RESISTANT STRAINS OF STAPHYLOCOCCUS-AUREUS [J].

GERBERDING, JL ;

MIICK, C ;

LIU, HH ;

CHAMBERS, HF .

ANTIMICROBIAL AGENTS AND CHEMOTHERAPY, 1991, 35 (12) :2574-2579

[10] Correlation between genotype and phenotypic categorization of staphylococci based on methicillin susceptibility and resistance [J].

Gradelski, E ;

Valera, L ;

Aleksunes, L ;

Bonner, D ;

Fung-Tomc, J .

JOURNAL OF CLINICAL MICROBIOLOGY, 2001, 39 (08) :2961-2963