Functional group transformations of diols, cyclic ethers, and Lactones using aqueous hydrobromic acid and phase transfer catalyst under microwave irradiation

被引：24

作者：

Kad, GL ^{[1
]}

Kaur, I ^{[1
]}

Bhandari, M ^{[1
]}

Singh, J ^{[1
]}

Kaur, J ^{[1
]}

机构：

[1] Panjab Univ, Dept Chem, Chandigarh 160014, India

来源：

ORGANIC PROCESS RESEARCH & DEVELOPMENT | 2003年 / 7卷 / 03期

关键词：

D O I：

10.1021/op025606h

中图分类号：

O69 [应用化学];

学科分类号：

081704 ;

摘要：

Synthesis of bromoalkanols has been achieved from diols, ethers, and lactones using aq HBr (48%) and tetrabutylammonium iodide/bromide as phase transfer catalyst under microwave irradiation. This environmentally benign route provides enhanced yields of products and does away with the use of benzene as compared to existing conventional methods.

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收藏

页码：339 / 340

页数：2

相关论文

共 15 条

[1] CONVENIENT STEREOSELECTIVE ROUTE TO THE SEX-PHEROMONE OF THE RED BOLLWORM MOTH VIA AN ALLYLIC SULFENATE TO SULFOXIDE REARRANGEMENT [J].

BABLER, JH ;

INVERGO, BJ .

JOURNAL OF ORGANIC CHEMISTRY, 1979, 44 (21) :3723-3724

[2] Thermolysis improvements in retro-Diels-Alder reactions of benzylamino alcohols under microwave irradiation [J].

Bortolussi, M ;

Bloch, R ;

Loupy, A .

JOURNAL OF CHEMICAL RESEARCH-S, 1998, (01) :34-35

[3]

Kad GL, 1996, J CHEM RES, P188

[4] Selective preparation of benzylic bromides in dry media coupled with microwave irradiation. [J].

Kad, GL ;

Singh, V ;

Kaur, KP ;

Singh, J .

TETRAHEDRON LETTERS, 1997, 38 (06) :1079-1080

[5]

KANG SK, 1985, SYNTHESIS-STUTTGART, P1161

[6] New solvent free organic synthesis using focused microwaves [J].

Loupy, A ;

Petit, A ;

Hamelin, J ;

Texier-Boullet, F ;

Jacquault, P ;

Mathé, D .

SYNTHESIS-STUTTGART, 1998, (09) :1213-1234

[7]

MARTINEZ AG, 1983, SYNTHESIS-STUTTGART, P663

[8] SIMPLE SYNTHESIS OF SEX-PHEROMONES OF CODLING MOTH AND RED BOLLWORM MOTH BY COUPLING OF GRIGNARD-REAGENTS WITH ALLYLIC HALIDES [J].

MORI, K .

TETRAHEDRON, 1974, 30 (20) :3807-3810

[9] LiCl catalyzed Knoevenagel condensation: Comparative study of conventional method vs microwave irradiation [J].

Sabitha, G ;

Reddy, BVS ;

Babu, RS ;

Yadav, JS .

CHEMISTRY LETTERS, 1998, (08) :773-774

[10] Selective oxidation of allylic methyl groups over a solid support under microwave irradiation [J].

Singh, J ;

Sharma, M ;

Kad, GL ;

Chhabra, BR .

JOURNAL OF CHEMICAL RESEARCH, 1997, (07) :264-265