Vascular status and physical functioning: the association between vascular status and physical functioning in middle-aged and elderly men: a cross-sectional study

被引：10

作者：

Arts, Ilse E. M. A. ^{[1
,2
]}

Schuurmans, Marieke J. ^{[2
]}

Grobbee, Diederick E. ^{[1
]}

van der Schouw, Yvonne T. ^{[1
]}

机构：

[1] UMC Utrecht, Julius Ctr Hlth Sci & Primary Care, NL-3508 GA Utrecht, Netherlands

[2] Hogesch Utrecht, Fac Chair Care Chronically & Elderly 3, Utrecht, Netherlands

来源：

EUROPEAN JOURNAL OF CARDIOVASCULAR PREVENTION & REHABILITATION | 2010年 / 17卷 / 02期

关键词：

cardiovascular disease; functionally-impaired elderly; middle-aged; INTIMA-MEDIA THICKNESS; CARDIOVASCULAR-DISEASE; ARTERIAL-DISEASE; DISABILITY; ATHEROSCLEROSIS; TORCETRAPIB; PERFORMANCE; STIFFNESS; STRENGTH; ADULTS;

D O I：

10.1097/HJR.0b013e3283348ec0

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

Background Living independently is an important component of quality of life. Cardiovascular diseases are prominent among the chronic conditions that predispose elderly people to functional limitations and disability, which impair quality of life. Insight into factors that play a role in the development process of limitations and disability of patients with subclinical cardiovascular diseases will aid in the development of preventive interventions. The aim of this study was to investigate the association of vascular status with muscle strength and physical functioning in middle aged and elderly men. Design The study is a population-based cross-sectional study in 400 men aged 40-80 years, independently living at the time of enrolment, performed in the University Medical Center Utrecht in The Netherlands. Methods Vascular status was measured noninvasively with ankle arm index, pulse wave velocity and intima-media thickness. Muscle strength was measured by isometric grip strength and physical performance was measured by Guralniks Physical Performance Score. Results After adjustment for confounders, no associations were found between vascular status and physical functioning. Stratifying did not reveal subgroups, such as older age, in which an association was present. Conclusion Contrary to former study results, this study showed no age-independent association between the extent of vascular damage and physical performance and muscle strength. Eur J Cardiovasc Prev Rehabil 17: 211-216 (C) 2010 The European Society of Cardiology

引用

页码：211 / 216

页数：6

共 28 条

[1]

Abate M, 2007, Eura Medicophys, V43, P407

[2] Torcetrapib and carotid intima-media thickness in mixed dyslipidaemia (RADIANCE 2 study): a randomised, double-blind trial [J].

Bots, Michiel L. ;

Visseren, Frank L. ;

Evans, Gregory W. ;

Riley, Ward A. ;

Revkin, James H. ;

Tegeler, Charles H. ;

Shear, Charles L. ;

Duggan, William T. ;

Vicari, Ralph M. ;

Grobbee, Diederick E. ;

Kastelein, John J. .

LANCET, 2007, 370 (9582) :153-160

[3] Common carotid artery intima-media thickness, carotid plaques, and walking speed [J].

Elbaz, A ;

Ripert, M ;

Tavernier, B ;

Février, B ;

Zureik, M ;

Gariépy, J ;

Alpérovitch, A ;

Tzourio, C .

STROKE, 2005, 36 (10) :2198-2202

[4] Volumetric and areal bone mineral density measures are associated with cardiovascular disease in older men and women: The health, aging, and body composition study [J].

Farhat, G. N. ;

Strotmeyer, E. S. ;

Newman, A. B. ;

Sutton-Tyrrell, K. ;

Bauer, D. C. ;

Harris, T. ;

Johnson, K. C. ;

Taaffe, D. R. ;

Cauley, J. A. .

CALCIFIED TISSUE INTERNATIONAL, 2006, 79 (02) :102-111

[5] Disability in older adults: Evidence regarding significance, etiology, and risk [J].

Fried, LP ;

Guralnik, JM .

JOURNAL OF THE AMERICAN GERIATRICS SOCIETY, 1997, 45 (01) :92-100

[6] Lower extremity function and subsequent disability: Consistency across studies, predictive models, and value of gait speed alone compared with the short physical performance battery [J].

Guralnik, JM ;

Ferrucci, L ;

Pieper, CF ;

Leveille, SG ;

Markides, KS ;

Ostir, GV ;

Studenski, S ;

Berkman, LF ;

Wallace, RB .

JOURNALS OF GERONTOLOGY SERIES A-BIOLOGICAL SCIENCES AND MEDICAL SCIENCES, 2000, 55 (04) :M221-M231

[7] A SHORT PHYSICAL PERFORMANCE BATTERY ASSESSING LOWER-EXTREMITY FUNCTION - ASSOCIATION WITH SELF-REPORTED DISABILITY AND PREDICTION OF MORTALITY AND NURSING-HOME ADMISSION [J].

GURALNIK, JM ;

SIMONSICK, EM ;

FERRUCCI, L ;

GLYNN, RJ ;

BERKMAN, LF ;

BLAZER, DG ;

SCHERR, PA ;

WALLACE, RB .

JOURNALS OF GERONTOLOGY, 1994, 49 (02) :M85-M94

[8]

Harrell F. E., 2001, Regression modelling strategies: with applications to linear models, logistic regression, and survival analysis, DOI DOI 10.1007/978-1-4757-3462-1

[9] Clinical use of carotid intima-media thickness: Review of the literature [J].

Hurst, R. Todd ;

Ng, Daniel W. C. ;

Kendall, Chris ;

Kiandheria, Bijoy .

JOURNAL OF THE AMERICAN SOCIETY OF ECHOCARDIOGRAPHY, 2007, 20 (07) :907-914

[10] Ill or just old? Towards a conceptual framework of the relation between ageing and disease [J].

Gerbrand J Izaks ;

Rudi GJ Westendorp .

BMC Geriatrics, 3 (1)

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