Mathematical modelling of respiratory syncytial virus (RSV): vaccination strategies and budget applications

被引：42

作者：

Acedo, L. ^{[1
]}

Diez-Domingo, J. ^{[2
]}

Morano, J. -A. ^{[1
]}

Villanueva, R. -J. ^{[1
]}

机构：

[1] Univ Politecn Valencia, Inst Matemat Multidisciplinar, Valencia 46022, Spain

[2] CSISP, Valencia, Spain

来源：

EPIDEMIOLOGY AND INFECTION | 2010年 / 138卷 / 06期

关键词：

Cost-effectiveness study; respiratory syncytial virus; vaccine policy development; TRANSMISSION DYNAMICS; BRONCHIOLITIS; INFECTIONS; PNEUMONIA; COMMUNITY; DISEASE;

D O I：

10.1017/S0950268809991373

中图分类号：

R1 [预防医学、卫生学];

学科分类号：

100235 [预防医学];

摘要：

We propose an age-structured mathematical model for respiratory syncytial virus in which children aged <1 year are especially considered. Real data on hospitalized children in the Spanish region of Valencia were used in order to determine some seasonal parameters of the model. Weekly predictions of the number of children aged <1 year that will be hospitalized in the following years in Valencia are presented using this model. Results are applied to estimate the regional cost of paediatric hospitalizations and to perform a cost-effectiveness analysis of possible vaccination strategies.

引用

页码：853 / 860

页数：8

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