Ethanolic extracts of Euphorbia and other ethnobotanical species as inhibitors of human tumour cell growth

被引：65

作者：

Whelan, LC ^{[1
]}

Ryan, MF ^{[1
]}

机构：

[1] Univ Coll Dublin, Dept Zool, Dublin 4, Ireland

来源：

PHYTOMEDICINE | 2003年 / 10卷 / 01期

关键词：

antineoplastic activity; A549; HEp-2; plant extracts;

D O I：

10.1078/094471103321648665

中图分类号：

Q94 [植物学];

学科分类号：

071001 [植物学];

摘要：

Ethanolic extracts of 20 plant species, selected from the ethnobotanical literature, were analysed for their pharmacological potential as antineoplastic agents against the HEp-2 cell line. Psoralea corylifolia and E. grandidens were the most efficacious species eliciting IC50 values of 22 mug/ml and 57 mug/ml respectively. Psoralea corylifolia, additionally tested against lung carcinoma (A549) cells gave an IC50 value of 68 mug/ml. Such data would justify a search for active compounds from this species.

引用

页码：53 / 58

页数：6

共 22 条

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FLOW-CYTOMETRIC ANALYSIS OF THE EFFECT OF BERBERINE ON THE EXPRESSION OF GLUCOCORTICOID RECEPTORS IN HUMAN HEPATOMA HEPG2 CELLS [J].