Synthesis of C2-symmetric dibenzyldiamino diols by double stereoselective Grignard addition to (S,S)-tartraldehyde dinitrone

被引:10
作者
Dondoni, A [1 ]
Perrone, D [1 ]
Rinaldi, M [1 ]
机构
[1] Univ Ferrara, Dipartimento Chim, Chim Organ Lab, I-44100 Ferrara, Italy
关键词
D O I
10.1016/S0040-4039(98)00330-X
中图分类号
O62 [有机化学];
学科分类号
070303 ; 081704 ;
摘要
A new asymmetric two-dimensional synthesis of 1,4-diamino 2,3-diols is illustrated by double addition of benzylmagnesium chloride to the bis-nitrone derived from (R,R)-tartraldehyde and reduction of the resulting dihydroxylamines. (C) 1998 Elsevier Science Ltd. All rights reserved.
引用
收藏
页码:2651 / 2654
页数:4
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