PDZ domains in synapse assembly and signalling

被引：463

作者：

Garner, CC ^{[1
]}

Nash, J

Huganir, RL

机构：

[1] Univ Alabama, Dept Neurobiol, Birmingham, AL 35294 USA

[2] Johns Hopkins Univ, Sch Med, Howard Hughes Med Inst, Dept Neurosci, Baltimore, MD 21205 USA

来源：

TRENDS IN CELL BIOLOGY | 2000年 / 10卷 / 07期

关键词：

D O I：

10.1016/S0962-8924(00)01783-9

中图分类号：

Q2 [细胞生物学];

学科分类号：

071009 ; 090102 ;

摘要：

Synaptic junctions are highly specialized structures designed to promote the rapid and efficient transmission of signals from the presynaptic terminal to the postsynaptic membrane within the central nervous system. Proteins containing PDZ domains play a fundamental organizational role at both the pre- and postsynaptic plasma membranes. This review focuses oil recent advances in our understanding of the mechanisms underlying the assembly of synapses in the central nervous system.

引用

页码：274 / 280

页数：7

共 75 条

[1] Kalirin, a cytosolic protein with spectrin-like and GDP/GTP exchange factor-like domains that interacts with peptidylglycine alpha-amidating monooxygenase, an integral membrane peptide-processing enzyme
Alam, MR
Johnson, RC
Darlington, DN
Hand, TA
Mains, RE
Eipper, BA
[J]. JOURNAL OF BIOLOGICAL CHEMISTRY, 1997, 272 (19) : 12667 - 12675
[2] Proline-rich synapse-associated proteins ProSAP1 and ProSAP2 interact with synaptic proteins of the SAPAP/GKAP family
Boeckers, TM
Winter, C
Smalla, KH
Kreutz, MR
Bockmann, J
Seidenbecher, C
Garner, CC
Gundelfinger, ED
[J]. BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS, 1999, 264 (01) : 247 - 252
[3] Boeckers TM, 1999, J NEUROSCI, V19, P6506
[4] Sorting out genes that regulate epithelial and neuronal polarity
Bredt, DS
[J]. CELL, 1998, 94 (06) : 691 - 694
[5] EphrinB ligands recruit GRIP family PDZ adaptor proteins into raft membrane microdomains
Brückner, K
Labrador, JP
Scheiffele, P
Herb, A
Seeburg, PH
Klein, R
[J]. NEURON, 1999, 22 (03) : 511 - 524
[6] Synapse maturation and structural plasticity at Drosophila neuromuscular junctions
Budnik, V
[J]. CURRENT OPINION IN NEUROBIOLOGY, 1996, 6 (06) : 858 - 867
[7] A tripartite protein complex with the potential to couple synaptic vesicle exocytosis to cell adhesion in brain
Butz, S
Okamoto, M
Südhof, TC
[J]. CELL, 1998, 94 (06) : 773 - 782
[8] Crystal structure of a PDZ domain
Cabral, JHM
Petosa, C
Sutcliffe, MJ
Raza, S
Byron, O
Poy, F
Marfatia, SM
Chishti, AH
Liddington, RC
[J]. NATURE, 1996, 382 (6592) : 649 - 652
[9] A kinase-regulated PDZ-domain interaction controls endocytic sorting of the β2-adrenergic receptor
Cao, TT
Deacon, HW
Reczek, D
Bretscher, A
von Zastrow, M
[J]. NATURE, 1999, 401 (6750) : 286 - 290
[10] Rapid redistribution of glutamate receptors contributes to long-term depression in hippocampal cultures
Carroll, RC
Lissin, DV
von Zastrow, M
Nicoll, RA
Malenka, RC
[J]. NATURE NEUROSCIENCE, 1999, 2 (05) : 454 - 460

← 1 2 3 4 5 6 7 8 →