One year follow-up of parkinsonism in dementia with Lewy bodies

被引：26

作者：

Ballard, C

O'Brien, J

Swann, A

Neill, D

Lantos, P

Holmes, C

Burn, D

Ince, P

Perry, R

McKeith, I

机构：

[1] Newcastle Gen Hosp, MRC, Neurochem Pathol Unit, Newcastle Upon Tyne NE4 6BE, Tyne & Wear, England

[2] Univ Newcastle Upon Tyne, Newcastle Upon Tyne NE1 7RU, Tyne & Wear, England

[3] Inst Psychiat, London, England

[4] Univ Southampton, Southampton SO9 5NH, Hants, England

来源：

DEMENTIA AND GERIATRIC COGNITIVE DISORDERS | 2000年 / 11卷 / 04期

关键词：

dementia with Lewy bodies; parkinsonism; progression;

D O I：

10.1159/000017240

中图分类号：

R592 [老年病学]; C [社会科学总论];

学科分类号：

03 ; 0303 ; 100203 ;

摘要：

The progression of parkinsonism over 1 year was evaluated in a prospective cohort of patients (n = 338), suffering from dementia with Lewy bodies (DLB), Alzheimer's disease (AD) or vascular dementia (VaD). Parkinsonism was assessed using the modified Unified Parkinson's Disease Rating Scale. Significant parkinsonism was significantly commoner in DLB sufferers (71%) than amongst patients with AD (7%) or VaD (10%). DLB patients with established parkinsonism had an annual increase in severity of 9%, but progression was more rapid (49% in 1 year) in patients with early parkinsonism. Parkinsonism was frequent at ail severities in DLB patients, but usually only present in other dementias when MMSE<10. Copyright (C) 2000 S. Karger AG, Basel.

引用

页码：219 / 222

页数：4

共 29 条

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