Osteoporosis in Crisis: It's Time to Focus on Fracture

被引:67
作者
Binkley, Neil [1 ]
Blank, Robert D. [2 ,3 ]
Leslie, William D. [4 ]
Lewiecki, E. Michael [5 ]
Eisman, John A. [6 ,7 ,8 ,9 ]
Bilezikian, John P. [10 ]
机构
[1] Univ Wisconsin, Osteoporosis Clin Res Program, 2870 Univ Ave, Madison, WI 53706 USA
[2] Med Coll Wisconsin, Milwaukee, WI 53226 USA
[3] Clement J Zablocki VAMC, Milwaukee, WI USA
[4] Univ Manitoba, Winnipeg, MB, Canada
[5] New Mexico Clin Res & Osteoporosis Ctr, Albuquerque, NM USA
[6] Garvan Inst Med Res, Darlinghurst, NSW, Australia
[7] Univ Notre Dame Australia, Sch Med Sydney, Sydney, NSW, Australia
[8] St Vincents Hosp, Sydney, NSW, Australia
[9] UNSW Australia, Sydney, NSW, Australia
[10] Columbia Univ, Coll Phys & Surg, New York, NY USA
关键词
FRACTURE; OSTEOPOROSIS; FALLS; DYSMOBILITY; BONE-MINERAL DENSITY; HIP FRACTURE; POSTURAL STABILITY; TRAUMA FRACTURES; RISK; MEN; WOMEN; FRAX; ASSOCIATION; MORTALITY;
D O I
10.1002/jbmr.3182
中图分类号
R5 [内科学];
学科分类号
100201 [内科学];
摘要
A crisis in osteoporosis treatment exists; the majority of those who sustain fracture do not receive treatment to reduce future fracture risk. This crisis presents an opportunity to focus the field from osteoporosis to fracture, the outcome of consequence. Proposed here is a change in focus suggesting that 1) attempts to define the level of trauma leading to fracture are counterproductive and that all fractures in older adults merit consideration of evaluation and 2) bone loss is not the entire problem but rather part of a broader syndrome including osteoporosis, sarcopenia, and other factors leading to fracture. With this approach, all fractures in older adults should be evaluated for potential lifestyle, non-pharmacological, and pharmacological interventions that could be implemented to reduce the risk of fracture recurrence. (C) 2017 American Society for Bone and Mineral Research.
引用
收藏
页码:1391 / 1394
页数:4
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