Pathologic evidence of arrhythmogenic cardiomyopathy and myocarditis in two siblings

被引：9

作者：

d'Amati, G

Fiore, F

Giordano, C

De Biase, L

Laurenti, A

Gallo, P

机构：

[1] Univ Aquila, Dept Expt Med, I-67100 Laquila, Italy

[2] Univ Rome La Sapienza, Dept Expt Med & Pathol, Rome, Italy

[3] Univ Rome La Sapienza, Inst Cardiac Surg, Rome, Italy

来源：

CARDIOVASCULAR PATHOLOGY | 1998年 / 7卷 / 01期

关键词：

D O I：

10.1016/S1054-8807(97)00063-X

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

This report describes the case of two siblings who underwent heart transplantation with a clinical diagnosis of mildly dilated cardiomyopathy. Pathological examination of the hearts revealed arrhythmogenic (right ventricular) cardiomyopathy. adipose type, associated with biventricular myocarditis in both the recipients' hearts. Family history revealed the occurrence of dilated cardiomyopathy and myocarditis in their father and his sister. To our knowledge, this is the first pathological demonstration of arrhythmogenic cardiomyopathy and myocarditis in siblings. We think this report substantiates a genetic ground for the relationship between these two heart conditions. (C) 1998 by Elsevier Science Inc.

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页码：39 / 46

页数：8

相关论文

共 16 条

[1] Arrhythmogenic right ventricular cardiomyopathy - Dysplasia, dystrophy, or myocarditis? [J].

Basso, C ;

Thiene, G ;

Corrado, D ;

Angelini, A ;

Nava, A ;

Valente, M .

CIRCULATION, 1996, 94 (05) :983-991

[2]

FONTALIRAN F, 1995, ARCH MAL COEUR VAISS, V88, P1021

[3] PATHOLOGICAL EVIDENCE OF EXTENSIVE LEFT-VENTRICULAR INVOLVEMENT IN ARRHYTHMOGENIC RIGHT VENTRICULAR CARDIOMYOPATHY [J].

GALLO, P ;

DAMATI, G ;

PELLICCIA, F .

HUMAN PATHOLOGY, 1992, 23 (08) :948-952

[4] ARRHYTHMOGENIC RIGHT-VENTRICULAR DYSPLASIA CARDIOMYOPATHY - A REVIEW [J].

MARCUS, FI ;

FONTAINE, G .

PACE-PACING AND CLINICAL ELECTROPHYSIOLOGY, 1995, 18 (06) :1298-1314

[5] COXSACKIE VIRUS-B3 PERIMYOCARDITIS IN BALB-C MICE - EXPERIMENTAL-MODEL OF CHRONIC PERIMYOCARDITIS IN THE RIGHT VENTRICLE [J].

MATSUMORI, A ;

KAWAI, C .

JOURNAL OF PATHOLOGY, 1980, 131 (02) :97-106

[6]

MCKENNA WJ, 1994, BRIT HEART J, V71, P215

[7] CLINICAL AND PATHOLOGIC FINDINGS OF MYOCARDITIS IN 2 FAMILIES WITH DILATED CARDIOMYOPATHY [J].

OCONNELL, JB ;

FOWLES, RE ;

ROBINSON, JA ;

SUBRAMANIAN, R ;

HENKIN, RE ;

GUNNAR, RM .

AMERICAN HEART JOURNAL, 1984, 107 (01) :127-135

[8] LEFT-VENTRICULAR INVOLVEMENT IN RIGHT VENTRICULAR DYSPLASIA [J].

PINAMONTI, B ;

SINAGRA, G ;

SALVI, A ;

DILENARDA, A ;

MORGERA, T ;

SILVESTRI, F ;

BUSSANI, R ;

CAMERINI, F .

AMERICAN HEART JOURNAL, 1992, 123 (03) :711-724

[9] Familial right ventricular dysplasia with biventricular involvement and inflammatory infiltration [J].

Pinamonti, B ;

Miani, D ;

Sinagra, G ;

Bussani, R ;

Silvestri, F ;

Camerini, F ;

DiLenarda, A ;

Lardieri, G ;

Mestroni, L ;

Morgera, T ;

Perkan, A ;

Rakar, S ;

Salvatore, L ;

Secoli, G ;

Zecchin, M .

HEART, 1996, 76 (01) :66-69

[10] A NEW LOCUS FOR ARRHYTHMOGENIC RIGHT-VENTRICULAR CARDIOMYOPATHY (ARVD2) MAPS TO CHROMOSOME 1Q42-Q43 [J].

RAMPAZZO, A ;

NAVA, A ;

ERNE, P ;

EBERHARD, M ;

VIAN, E ;

SLOMP, P ;

TISO, N ;

THIENE, G ;

DANIELI, GA .

HUMAN MOLECULAR GENETICS, 1995, 4 (11) :2151-2154