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Melanin and virulence in Cryptococcus neoformans

被引：233
作者：
Casadevall, A
Rosas, AL
Nosanchuk, JD
机构：
[1] Yeshiva Univ Albert Einstein Coll Med, Dept Microbiol & Immunol, Bronx, NY 10461 USA
[2] Yeshiva Univ Albert Einstein Coll Med, Dept Med, Bronx, NY 10461 USA
来源：
CURRENT OPINION IN MICROBIOLOGY | 2000年 / 3卷 / 04期
关键词：
D O I：
10.1016/S1369-5274(00)00103-X
中图分类号：
Q93 [微生物学];
学科分类号：
071005 ; 100705 ;
摘要：
Melanin synthesis has been associated with Virulence for the human pathogenic fungus Cryptococcus neoformans. Recent evidence indicates that C. neoformans cells synthesize melanin during infection and that this pigment protects the fungus against immune defense mechanisms.
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页码：354 / 358
页数：5
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