Death to a blood vessel, death to a tumor

被引:25
作者
Cheresh, DA [1 ]
机构
[1] Scripps Res Inst, Dept Immunol, La Jolla, CA 92037 USA
[2] Scripps Res Inst, Dept Vasc Biol, La Jolla, CA 92037 USA
关键词
D O I
10.1038/nm0498-395
中图分类号
Q5 [生物化学]; Q7 [分子生物学];
学科分类号
071010 ; 081704 ;
摘要
Suppression of endothelial cell αVβ3 activity by TNF and IFN-γ disrupts angiogenesis and promotes the demise of malignant melanoma (pages 408–414).
引用
收藏
页码:395 / 396
页数:2
相关论文
共 10 条
  • [1] REQUIREMENT OF VASCULAR INTEGRIN ALPHA(V)BETA(3) FOR ANGIOGENESIS
    BROOKS, PC
    CLARK, RAF
    CHERESH, DA
    [J]. SCIENCE, 1994, 264 (5158) : 569 - 571
  • [2] INTEGRIN ALPHA(V)BETA(3) ANTAGONISTS PROMOTE TUMOR-REGRESSION BY INDUCING APOPTOSIS OF ANGIOGENIC BLOOD-VESSELS
    BROOKS, PC
    MONTGOMERY, AMP
    ROSENFELD, M
    REISFELD, RA
    HU, TH
    KLIER, G
    CHERESH, DA
    [J]. CELL, 1994, 79 (07) : 1157 - 1164
  • [3] Biology of chemokine and classical chemoattractant receptors: Differential requirements for adhesion-triggering versus chemotactic responses in lymphoid cells
    Campbell, JJ
    Qin, SX
    Bacon, KB
    Mackay, CR
    Butcher, EC
    [J]. JOURNAL OF CELL BIOLOGY, 1996, 134 (01) : 255 - 266
  • [4] ELICIERI BP, IN PRESS J CELL BIOL
  • [5] DEFINITION OF 2 ANGIOGENIC PATHWAYS BY DISTINCT ALPHA(V) INTEGRINS
    FRIEDLANDER, M
    BROOKS, PC
    SHAFFER, RW
    KINCAID, CM
    VARNER, JA
    CHERESH, DA
    [J]. SCIENCE, 1995, 270 (5241) : 1500 - 1502
  • [6] GUTHEIL JC, IN PRESS P AM SOC CL
  • [7] Evidence for the involvement of endothelial cell integrin αVβ3 in the disruption of the tumor vasculature induced by TNF and IFN-γ
    Rüegg, C
    Yilmaz, A
    Bieler, G
    Bamat, J
    Chaubert, P
    Lejeune, FJ
    [J]. NATURE MEDICINE, 1998, 4 (04) : 408 - 414
  • [8] Suppression of p53 activity and p21(WAF1/CIP1) expression by vascular cell integrin alpha v beta 3 during angiogenesis
    Stromblad, S
    Becker, JC
    Yebra, M
    Brooks, PC
    Cheresh, DA
    [J]. JOURNAL OF CLINICAL INVESTIGATION, 1996, 98 (02) : 426 - 433
  • [9] VASSBOTN FS, 1994, J BIOL CHEM, V269, P13874
  • [10] Time-dependent vascular regression and permeability changes in established human tumor xenografts induced by an anti-vascular endothelial growth factor vascular permeability factor antibody
    Yuan, F
    Chen, Y
    Dellian, M
    Safabakhsh, N
    Ferrara, N
    Jain, RK
    [J]. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 1996, 93 (25) : 14765 - 14770