Analysis of acidic drugs in Swiss wastewaters

被引：60

作者：

Soulet, B ^{[1
]}

Tauxe, A ^{[1
]}

Tarradellas, J ^{[1
]}

机构：

[1] Ecole Polytech Fed Lausanne, ENAC, ISTE, CECOTOX, CH-1015 Lausanne, Switzerland

来源：

INTERNATIONAL JOURNAL OF ENVIRONMENTAL ANALYTICAL CHEMISTRY | 2002年 / 82卷 / 10期

关键词：

nonsteroidal anti-inflammatory drugs; lipid regulating agent metabolite; wastewater; sewage treatment plant;

D O I：

10.1080/0306731021000075384

中图分类号：

O65 [分析化学];

学科分类号：

070302 ; 081704 ;

摘要：

Five acidic drugs (clofibric acid, ibuprofen, ketoprofen, mefenamic acid and diclofenac) were chosen in order to determine their behavior in a sewage treatment plant (STP). An analytical method using solid phase extraction (SPE) and a gas chromatograph coupled with a mass spectrometer (GC-MS) was used. The results show that four pharmaceuticals (clofibric acid, ketoprofen, mefenamic acid and diclofenac) are not well removed by treatment in Swiss STPs. Maximum concentration in the effluent was determined for mefenamic acid up to 1.0 mug/L. This component seems to be relevant in Swiss STPs effluents and we can expect its presence in surface waters.

引用

页码：659 / 667

页数：9

共 14 条

[1]

[Anonymous], 1989, MARTINDALE EXTRA PHA

[2] Occurrence of the pharmaceutical drug clofibric acid and the herbicide mecoprop in various Swiss lakes and in the North Sea [J].

Buser, HR ;

Muller, MD ;

Theobald, N .

ENVIRONMENTAL SCIENCE & TECHNOLOGY, 1998, 32 (01) :188-192

[3] Occurrence and fate of the pharmaceutical drug diclofenac in surface waters: Rapid photodegradation in a lake [J].

Buser, HR ;

Poiger, T ;

Muller, MD .

ENVIRONMENTAL SCIENCE & TECHNOLOGY, 1998, 32 (22) :3449-3456

[4] Pharmaceuticals and personal care products in the environment: Agents of subtle change? [J].

Daughton, CG ;

Ternes, TA .

ENVIRONMENTAL HEALTH PERSPECTIVES, 1999, 107 :907-938

[5]

Garrison AW, 1976, IDENTIFICATION ANAL, V30, P517

[6] Occurrence, fate and effects of pharmaceutical substances in the environment - A review [J].

Halling-Sorensen, B ;

Nielsen, SN ;

Lanzky, PF ;

Ingerslev, F ;

Lutzhoft, HCH ;

Jorgensen, SE .

CHEMOSPHERE, 1998, 36 (02) :357-394

[7]

Heberer T, 1997, FRESEN ENVIRON BULL, V6, P438

[8] ANALYSIS OF PHENOXYCARBOXYLIC ACIDS AND OTHER ACIDIC COMPOUNDS IN TAP, GROUND, SURFACE AND SEWAGE WATER AT THE LOW NG/L LEVEL [J].

HEBERER, T ;

BUTZ, S ;

STAN, HJ .

INTERNATIONAL JOURNAL OF ENVIRONMENTAL ANALYTICAL CHEMISTRY, 1995, 58 (1-4) :43-53

[9]

HEBERER T, 1994, J AOAC INT, V77, P1587

[10] Occurrence of antibiotics in the aquatic environment [J].

Hirsch, R ;

Ternes, T ;

Haberer, K ;

Kratz, KL .

SCIENCE OF THE TOTAL ENVIRONMENT, 1999, 225 (1-2) :109-118

← 1 2 →