An unusual concurrence of graft versus host disease caused by engraftment of maternal lymphocytes with DiGeorge anomaly

被引：14

作者：

Ocejo-Vinyals, JG

Lozano, MJ

Sánchez-Velasco, P

de Diego, JE

Paz-Miguel, JE

Leyva-Cobián, F ^{[1
]}

机构：

[1] Hosp Univ Marques de Valdecilla, Serv Immunol, Inst Nacl Salud, Santander 39008, Spain

[2] Hosp Univ Marques de Valdecilla, Serv Pediat, Santander 39008, Spain

来源：

ARCHIVES OF DISEASE IN CHILDHOOD | 2000年 / 83卷 / 02期

关键词：

biclonal gammapathy; materno-fetal chimerism; graft versus host disease; DiCeorge anomaly; Omenn's syndrome; Evans' syndrome;

D O I：

10.1136/adc.83.2.165

中图分类号：

R72 [儿科学];

学科分类号：

100202 ;

摘要：

We describe a girl with DiGeorge anomaly and normal cytogenetic and molecular studies, whose clinical course was complicated by graft versus host disease caused by intrauterine materno-fetal transfusion, and several immunohaematological alterations including a monoclonal gammapathy of undetermined significance (first IgG, which subsequently changed to IgM). The main clinical features and pathological findings are discussed.

引用

页码：165 / 169

页数：5

共 30 条

[1]

APPLETON AL, 1994, BONE MARROW TRANSPL, V14, P157

[2]

ARCHER E, 1990, CUTIS, V45, P455

[3] ISOLATION OF A ZINC-FINGER GENE CONSISTENTLY DELETED IN DIGEORGE-SYNDROME [J].