Small G proteins as novel therapeutic targets in cardiovascular medicine

被引：16

作者：

Barandier, C ^{[1
]}

Ming, XF ^{[1
]}

Yang, ZH ^{[1
]}

机构：

[1] Univ Fribourg, Div Physiol, Dept Med, CH-1700 Fribourg, Switzerland

来源：

NEWS IN PHYSIOLOGICAL SCIENCES | 2003年 / 18卷

关键词：

D O I：

10.1152/nips.01407.2002

中图分类号：

Q4 [生理学];

学科分类号：

071003 ;

摘要：

Small G proteins are implicated in regulation of endothelial function, smooth muscle cell contraction, proliferation, and migration, as well as cardiomyocyte hypertrophy. Targeting small G proteins and their downstream signaling could constitute promising therapeutic approaches in cardiovascular disorders such as atherosclerosis, restenosis, hypertension, vasospasm, and cardiac hypertrophy.

引用

页码：18 / 22

页数：5

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