The calcium store in the nuclear envelope

被引：95

作者：

Petersen, OH ^{[1
]}

Gerasimenko, OV ^{[1
]}

Gerasimenko, JV ^{[1
]}

Mogami, H ^{[1
]}

Tepikin, AV ^{[1
]}

机构：

[1] Univ Liverpool, Physiol Lab, MRC, Secretory Control Res Grp, Liverpool L69 3BX, Merseyside, England

来源：

CELL CALCIUM | 1998年 / 23卷 / 2-3期

关键词：

D O I：

10.1016/S0143-4160(98)90106-3

中图分类号：

Q2 [细胞生物学];

学科分类号：

071009 ; 090102 ;

摘要：

The nuclear envelope has a relatively small volume, but is connected up to the vastly larger endoplasmic reticulum. The Ca2+ concentration in the lumen of the interconnected nuclear envelope and endoplasmic reticulum network is in the resting state maintained at a level of more than 100 mu M. There are specific Ca2+ release channels present in the inner nuclear membrane that can be activated by inositol trisphosphate or cADP ribose. The system, therefore, allows selective release of Ca2+ into the nucleoplasm which could be important for the control of specific types of gene expression.

引用

页码：87 / 90

页数：4

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