Biocompatible calcium phosphate based tubes

被引：19

作者：

Chandanshive, Balasaheb ^{[1
]}

Dyondi, Deepti ^{[2
]}

Ajgaonkar, Vishnu R. ^{[3
]}

Banerjee, Rinti ^{[2
]}

Khushalani, Deepa ^{[1
]}

机构：

[1] Tata Inst Fundamental Res, Mat Chem Grp, Dept Chem Sci, Bombay 400005, Maharashtra, India

[2] Indian Inst Technol, Dept Biosci & Bioengn, Ctr Res Nanotechnol & Sci, Bombay 400076, Maharashtra, India

[3] Univ Mumbai, Dept Chem, Bombay 400098, Maharashtra, India

来源：

JOURNAL OF MATERIALS CHEMISTRY | 2010年 / 20卷 / 33期

关键词：

ALUMINUM-OXIDE TEMPLATE; ANODIC ALUMINA; SCAFFOLD DESIGN; HYDROXYAPATITE; FABRICATION; NANOTUBES; NANOSTRUCTURES; NANOWIRES; ENERGY; GLASS;

D O I：

10.1039/c0jm00145g

中图分类号：

O64 [物理化学（理论化学）、化学物理学];

学科分类号：

070305 [高分子化学与物理];

摘要：

Porous anodic alumina template has been employed, in the presence of a precipitation reaction involving Ca(OH)(2) and H(3)PO(4), to form calcium phosphate based tubular structures. These structures are amorphous in nature and can be recovered by etching the sacrificial alumina membrane. Full characterization of these structures has been done using X-ray diffraction, electron microscopy and FTIR. In addition, their biocompatibility has been tested on L929 mouse fibroblast cells using MTT assay and the cellular internalization of these nanotubes has also been evaluated using rhodamine 6G dye tagged nanotubes in the presence of fibroblast cells. The studies also suggest that the nanotubes are non-toxic to fibroblasts and can be taken up easily by mammalian cells. Such tubes may serve as vehicles for drugs and growth factors, and for tissue repair including bone regeneration.

引用

页码：6923 / 6928

页数：6

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